Lubrication of an injection needle

1. A method for lubricating an injection needle when used multiple times at a single occasion to penetrate a human skin support, the method comprising:

a) depositing a layer of a lubricating composition on the human skin support; and

b) penetrating multiple times in a single occasion the layer of the lubricating composition deposited in step a) with an injection needle, thereby providing a lubricated injection needle having a deposited layer of the lubricating composition thereon, the number of times being more than 30, but less than or equal to 50,

wherein the injection needle is lubricated after each of the multiple times in the single occasion so as to maintain lubrication of the injection needle during the single occasion,

wherein the lubricating composition comprises silicone, and

wherein the lubricating composition comprises silicone in an amount within the range of from 25% to 30% by weight of the total composition.

2. The method according to claim 1 , wherein step a) is performed once.

3. The method according to claim 1 , wherein step b) is performed at least 10 times.

4. The method according to claim 1 , wherein the lubricating composition is sterile.

5. The method of claim 1 , wherein an amount of lubricating composition deposited on the human skin support is within the range of 0.01 g/cm 2 to 0.1 g/cm 2 .

6. The method of claim 1 , wherein the injection needle is lubricated after each of the multiple times in the single occasion so as to re-lubricate the needle multiple times.

7. The method of claim 1 , wherein:

the lubricating composition is penetrated prior to penetration of the human skin support, such that the lubricating composition is a first layer penetrated by the injection needle and the human skin support is a second layer penetrated by the injection needle.

8. The method of claim 7 , wherein a penetration angle between the injection needle and the lubricating composition is smaller than 90°.

9. The method of claim 1 , wherein the injection needle comprises a cutting edge and a hollow shaft.

10. The method of claim 9 , wherein:

when the injection needle is penetrating into the human skin support, a first penetration force acts in a first direction toward the cutting edge when the human skin support is penetrated by the cutting edge, and a second penetration force acts in a second direction along the hollow shaft and opposite to the first direction.

11. The method of claim 1 , wherein the injection needle comprises two grinding surfaces.

12. The method of claim 1 , wherein the lubricating composition comprises silicone in an amount of 25% by weight of the total composition.

13. A method for injecting multiple doses of an injectable composition into human skin at a single occasion, the method comprising:

a) depositing a layer of a lubricating composition on the skin;

b) penetrating multiple times in a single occasion the layer of the lubricating composition deposited in step a) with an injection needle, thereby providing a lubricated injection needle having a deposited layer of the lubricating composition thereon, the number of times being more than 30, but less than or equal to 50; and

c) injecting a dose of the injectable composition each time the injection needle penetrates the skin,

wherein the injection needle is lubricated after each of the multiple times in the single occasion so as to maintain lubrication of the injection needle during the single occasion,

wherein the lubricating composition comprises silicone, and

wherein the lubricating composition comprises silicone in an amount within the range of from 25% to 30% by weight of the total composition.

14. The method according to claim 13 , wherein the injectable composition is selected from a filler and a toxin composition.

15. The method according to claim 14 , wherein the injectable composition is a filler composition containing a filler selected from hyaluronic acid and derivatives thereof, in linear or cross-linked form, collagen, poly acrylamide, calcium hydroxyl apatite, poly lactide acid, and poly (methyl metacrylate).

16. The method according to claim 15 , wherein the filler is cross-linked hyaluronic acid.

17. The method according to claim 14 , wherein the injectable composition is a toxin composition containing botulinum toxin.

18. The method according to claim 13 , wherein the method is a cosmetic treatment method.

19. The method of claim 13 , wherein the lubricating composition comprises silicone in an amount of 25% by weight of the total composition.