Incubator apparatus and methods
Apparatus and methods for monitoring embryos in an incubator are described. The apparatus comprises an incubation chamber defined by an incubation chamber housing and a slide carrier comprising a plurality of compartment walls that define compartments for holding embryo slides within the incubation chamber for incubation. The slide carrier is moveable, for example by rotation, relative to the incubation chamber housing to allow a selected compartment to be moved to a loading position defined at least in part by a loading port wall associated with the incubation chamber housing. The loading port wall is arranged to cooperate with the wall of a compartment in the loading position to restrict the extent to which the environment of the compartment in the loading position is in fluid communication with the environments of other compartments in the incubation chamber.
1. An incubator for embryos supported on embryo slides, the incubator comprising:
an incubation chamber defined by an incubation chamber housing; and
a slide carrier comprising a plurality of compartment walls that define compartments for holding embryo slides within the incubation chamber for incubation, wherein the slide carrier is moveable relative to the incubation chamber housing to allow a selected compartment to be moved to a loading position defined at least in part by a loading port wall associated with the incubation chamber housing, and wherein the loading port wall is arranged to cooperate with a compartment wall of a compartment in the loading position to restrict the extent to which the environment of the compartment in the loading position is in fluid communication with the environments of other compartments in the incubation chamber, wherein the loading port wall is positioned to align with the compartment wall of a compartment in the loading position to restrict the extent to which the environment of the compartment in the loading position is in fluid communication with the environments of other compartments in the incubation chamber.
2. The incubator of claim 1 , wherein the environments of the compartments not in the loading position are in fluid communication such that there is a common incubation atmosphere for these compartments.
3. The incubator of claim 1 , wherein the slide carrier is moveable relative to the incubation chamber housing by rotation about a rotation axis.
4. The incubator of claim 3 , wherein compartment walls between adjacent compartments extend in a radial direction away from the rotation axis.
5. The incubator of claim 3 , wherein at least part of the loading port wall extends in a radial direction away from the rotation axis.
6. The incubator of claim 3 , wherein the compartments for receiving embryo slides comprise sectors arranged around an arc of a circle centred on the rotation axis.
7. The incubator of claim 1 , wherein the slide carrier is moveable relative to the incubation chamber housing by translation along a translation axis.
8. The incubator of claim 1 , further comprising a motor for driving the slide carrier relative to the incubation chamber housing.
9. The incubator of claim 8 , further comprising a controller adapted to control the motor to move a selected compartment to the loading position.
10. The incubator of claim 9 , wherein the controller is further adapted to select a compartment to be moved to the loading position in accordance with a predefined loading program.
11. The incubator of claim 1 , wherein the loading port wall is integrally formed with the incubation chamber housing.
12. An incubator for embryos supported on embryo slides, the incubator comprising:
an incubation chamber defined by an incubation chamber housing; and
a slide carrier comprising a plurality of compartment walls that define compartments for holding embryo slides within the incubation chamber for incubation, wherein the slide carrier is moveable relative to the incubation chamber housing to allow a selected compartment to be moved to a loading position defined at least in part by a loading port wall associated with the incubation chamber housing, and wherein the loading port wall is arranged to cooperate with a compartment wall of a compartment in the loading position to restrict the extent to which the environment of the compartment in the loading position is in fluid communication with the environments of other compartments in the incubation chamber, wherein the loading port wall is provided by a loading port insert coupled to the incubation chamber housing.
13. The incubator of claim 1 , further comprising a removable tray arranged beneath the slide carrier in a region of the loading position to collect fluid passing through any holes in the slide carrier in this region.
14. The incubator of claim 1 , further comprising an expandable member between the loading port wall and the compartment wall of the compartment in the loading position.
15. The incubator of claim 14 , wherein the expandable member comprises a drive connected to the loading port wall and the compartment wall of the compartment in the loading position.
16. An incubator for embryos supported on embryo slides, the incubator comprising:
an incubation chamber defined by an incubation chamber housing; and
a slide carrier comprising a plurality of compartment walls that define compartments for holding embryo slides within the incubation chamber for incubation, wherein the slide carrier is moveable relative to the incubation chamber housing to allow a selected compartment to be moved to a loading position defined at least in part by a loading port wall associated with the incubation chamber housing, and wherein the loading port wall is arranged to cooperate with a compartment wall of a compartment in the loading position to restrict the extent to which the environment of the compartment in the loading position is in fluid communication with the environments of other compartments in the incubation chamber, wherein an adjustment mechanism between the loading port wall and the compartment wall of the compartment in the loading position comprises an inflatable sealing element.
17. The incubator of claim 1 , further comprising a display for indicating an identity of a compartment in the loading position.
18. The incubator of claim 1 , further comprising a temperature control system of the slide carrier.
19. The incubator of claim 1 , further comprising a sensor within the incubation chamber.
20. The incubator of claim 1 , further comprising a loading port cover moveable from a closed position in which the loading port cover covers the loading position to an open position in which the loading port cover does not cover the loading position.
21. An incubator for embryos supported on embryo slides, the incubator comprising:
an incubation chamber defined by an incubation chamber housing; and
a slide carrier comprising a plurality of compartment walls that define compartments for holding embryo slides within the incubation chamber for incubation, wherein the slide carrier is moveable relative to the incubation chamber housing to allow a selected compartment to be moved to a loading position defined at least in part by a loading port wall associated with the incubation chamber housing, and wherein the loading port wall is arranged to cooperate with a compartment wall of a compartment in the loading position to restrict the extent to which the environment of the compartment in the loading position is in fluid communication with the environments of other compartments in the incubation chamber, further comprising a sealing element sealing a loading port cover between the loading position and an environment surrounding the incubator when the loading port cover is in a closed position.