IP Library Granted Patent US 10,287,618
Granted Patent B2
US 10,287,618 · App. 15/129,442 · Granted May 14, 2019

Wash monitor composition, device, and method of use

Inventors: Francois Ahimou (Woodbury, MN); RuthAnn R. Duda (Eagan, MN); G. Marco Bommarito (Stillwater, MN); Timothy J. Nies (Stillwater, MN); Kai Qiu (Shangahi, CN)
Assignee: 3M INNOVATIVE PROPERTIES COMPANY
C12Q1/22A61B90/70A61L2/04A61L2/18A61L2/28A61B2090/702A61L2202/17A61L2202/24
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Quick Facts
Patent No.
US 10,287,618
App. No.
15/129,442
Granted
May 14, 2019
Kind
B2
Abstract

A composition for monitoring the efficacy of a decontamination process is provided, the composition comprising a cellulose polymer and a predetermined quantity of an adenine nucleotide. A monitoring device comprising a test element with the composition disposed thereon is also provided. The composition and/or monitoring device can be used in a method. The method includes exposing the monitoring device to a decontamination process and subsequently measuring the residual tracer analyte on the monitoring device.

Claims (31)

1. A monitoring device, comprising:

a container comprising a first end with an opening dimensioned to receive a test element;

the test element disposed in the container, the test element comprising a test portion;

a dried composition releasably adhered to the test portion, the dried composition comprising a cellulose polymer, sugar, and a predetermined quantity of an adenine nucleotide, wherein the sugar and the cellulose polymer are present in the composition at a sugar:cellulose polymer mass ratio of about 9:1 to about 60:1, inclusive; and

a reagent for detecting the adenine nucleotide, the reagent disposed in the container.

2. The monitoring device of claim 1 , wherein the cellulose polymer comprises a water-soluble cellulose derivative.

3. The monitoring device of claim 1 , further comprising a secural element.

4. A kit, comprising the monitoring device of claim 1 .

5. The kit of claim 4 , further comprising a means to secure the test element.

6. The kit of claim 4 , further comprising an article comprising a receiver dimensioned to receive the test element and to restrict fluidic accessibility to the test portion.

7. A system, comprising:

a monitoring device, comprising:

a container comprising a first end with an opening dimensioned to receive a test element;

the test element disposed in the container, the test element comprising a test portion;

a dried composition releasably adhered to the test portion, the dried composition comprising a cellulose polymer, sugar, and a predetermined quantity of an adenine nucleotide, wherein the sugar and the cellulose polymer are present in the composition at a sugar:cellulose polymer mass ratio of about 9:1 to about 60:1, inclusive;

a reagent for detecting the adenine nucleotide, the reagent disposed in the container;

an analytical instrument for detecting a reaction between the adenine nucleotide and the reagent; and

a processor configured to receive electronic data from the analytical instrument.

8. A method of assessing the efficacy of a decontamination process, comprising:

exposing a test portion of a monitoring device to a decontamination process;

wherein the test portion includes a dried composition removably adhered thereto;

wherein the dried composition comprises a cellulose polymer, a sugar, and

a predetermined first quantity of an adenine nucleotide, wherein the sugar and the cellulose polymer are present in the composition at a sugar:cellulose polymer mass ratio of about 9:1 to about 60:1, inclusive;

after exposing the test portion to the decontamination process, contacting the test portion with a reagent for detecting the adenine nucleotide;

using the detection reagent to measure a second quantity of the adenine nucleotide remaining on the test portion; and

comparing the second quantity to a predetermined first threshold quantity.

9. The method of claim 8 , wherein comparing the second quantity to a predetermined threshold quantity further comprises comparing the second quantity to a plurality of predetermined threshold quantities.

10. The method of claim 9 , further comprising the steps of comparing the second quantity of adenine nucleotide to a second threshold quantity and reporting an outcome of an assessment of the efficacy:

wherein, when the second quantity is less than or equal to the first threshold quantity, the outcome of the decontamination process is reported to indicate the process was efficacious;

wherein, when the second quantity is greater than the first threshold quantity but less than or equal to a second threshold quantity, the outcome of the decontamination process is reported to indicate the process had a deficiency associated with a first predetermined parameter of the decontamination process.

11. The method of claim 8 , further comprising the step of placing the test portion of the monitoring device into a receiver configured to restrict fluidic accessibility to the test portion.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2024
From: 3M INNOVATIVE PROPERTIES COMPANY
To: SOLVENTUM INTELLECTUAL PROPERTIES COMPANY
Reel/Frame 066445/0328 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 27, 2016
From: AHIMOU, FRANCOIS; DUDA, RUTHANN R.; BOMMARITO, G. MARCO; NIES, TIMOTHY J.; QIU, KAI
To: 3M INNOVATIVE PROPERTIES COMPANY
Reel/Frame 039862/0648 →
Continuity (2)
Provisional Application 61971933 · Mar 28, 2014
Related Publication 20170175163A1 · Jun 22, 2017