METHODS AND SYSTEMS FOR DETERMINING SUBJECT-SPECIFIC PARAMETERS FOR A NEUROMODULATION THERAPY
A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.
1 . A system for monitoring a subject, the system comprising:
an acoustic sensor;
an accelerometer; and
a recording device coupled to the acoustic sensor and the accelerometer, wherein the recording device:
collects acoustic data from the acoustic sensor and acceleration data from the accelerometer;
measures a progression of a neurological disease of a subject using the acoustic data and the acceleration data; and
records progression data indicating the progression of the neurological disease.
2 . The system of claim 1 , wherein the acoustic data comprises of at least one of high frequency head vibration, muscle vibration or speech production.
3 . The system of claim 1 , further comprising a housing containing the acoustic sensor, the accelerometer and the recording device.
4 . The system of claim 1 , further comprising an external device, wherein the external device receives the progression data.
5 . The system of claim 4 , wherein the external device reports the progression of the neurological disease as a quantitative estimate.
6 . The system of claim 1 , wherein the acceleration data comprises of at least one of a magnitude of tremor, an absolute value of an acceleration of the subject's head, a normalized value of the acceleration of the subject's head or a frequency of occurrence of episodes of tremor.
7 . The system of claim 1 , further comprising a physiological sensor.
8 . The system of claim 7 , wherein the physiological sensor senses respiration of the subject.
9 . The system of claim 1 , wherein the recording device is further configured to measure the progression of the neurological disease by using at least one of a magnitude, a frequency of movement of a tremor, a duration or a frequency of occurrence of one or more tremor to measure a progression of epilepsy of the subject.
10 . A system for monitoring a subject, the system comprising:
an acoustic sensor;
an accelerometer;
a recording device coupled to the acoustic sensor and the accelerometer, wherein the recording device collects acoustic data from the acoustic sensor and acceleration data from the accelerometer; and
an external device, wherein the external device:
receives the acoustic data and the acceleration data from the recording device;
measures a progression of a neurological disease of a subject using the acoustic data and the acceleration data; and
records progression data indicating the progression of the neurological disease.
11 . The system of claim 10 , wherein the acoustic data comprises of at least one of high frequency head vibration, muscle vibration or speech production.
12 . The system of claim 10 , further comprising a housing containing the acoustic sensor, the accelerometer and the recording device.
13 . The system of claim 10 , wherein the external device is further configured to report the progression of the neurological disease as a quantitative estimate.
14 . The system of claim 10 , wherein the acceleration data comprises of at least one of a magnitude of tremor, an absolute value of an acceleration of the subject's head, a normalized value of the acceleration of the subject's head or a frequency of occurrence of episodes of tremor.
15 . The system of claim 10 , further comprising a physiological sensor.
16 . The system of claim 15 , wherein the physiological sensor senses respiration of the subject.
17 . The system of claim 10 , wherein the external device is configured to measure the progression of the neurological disease by using at least one of a magnitude, a frequency of movement of a tremor, a duration or a frequency of occurrence of one or more tremor to measure a progression of epilepsy of the subject.
18 . A method of monitoring a subject, the method comprising:
collecting acoustic data from an acoustic sensor;
collecting acceleration data from a accelerometer;
measuring, by a device implanted within a subject, a progression of a neurological disease of the subject using the acoustic data and the acceleration data; and
recording, by the device, progression data indicating the progression of the neurological disease.
19 . The method of claim 18 , further comprising transmitting, by the device, the progression of the neurological disease to an external device.
20 . The method of claim 18 , wherein measuring the progression of the neurological disease comprises using at least one of a magnitude, a frequency of movement of a tremor, a duration or a frequency of occurrence of one or more tremor to measure a progression of epilepsy of the subject.