IP Library Granted Patent US 9,694,195
Granted Patent B2
US 9,694,195 · App. 15/137,670 · Granted Jul 4, 2017

Low frequency neurostimulator for the treatment of neurological disorders

Inventors: David R. Fischell (Fair Haven, NJ); Adrian R. M. Upton (Hamilton, CA)
Assignee: NeuroPace, Inc.
A61N2/006A61N1/32A61N1/36021A61N1/36064A61N1/36071A61N2/02A61N1/36025A61N1/36082A61N2/008
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Quick Facts
Patent No.
US 9,694,195
App. No.
15/137,670
Granted
Jul 4, 2017
Kind
B2
Abstract

A system for treating neurological conditions by low-frequency time varying electrical stimulation includes an electrical device for applying such low-frequency energy, in a range below approximately 10 Hz, to the patient's brain tissue. An implantable embodiment applies direct electrical stimulation to electrodes implanted in or on the patient's brain, while a non-invasive embodiment causes a magnetic field to induce electrical currents in the patient's brain.

Claims (19)

1. A magnetic depolarizer for treating a neurological disorder of a patient through transcranial magnetic stimulation, the magnetic depolarizer comprising:

at least one magnetic coil;

a power source; and

control circuitry in operable communication with the power source and the at least one magnetic coil, the control circuitry configured to cause the at least one magnetic coil to deliver at least one magnetic pulse to the patient,

wherein the at least one magnetic pulse is provided by a carrier frequency having a low frequency signal modulated thereon.

2. The magnetic depolarizer of claim 1 wherein the control circuitry is further configured to set the duration of the at least one magnetic pulse to a duration between about 10 microseconds and 1,000 microseconds.

3. The magnetic depolarizer of claim 1 wherein the at least one magnetic pulse has an intensity of 0.1 to 10 Tesla.

4. The magnetic depolarizer of claim 1 wherein the power source comprises a rechargeable battery.

5. The magnetic depolarizer of claim 1 , wherein the carrier frequency is on the order of 100 Hz.

6. The magnetic depolarizer of claim 1 , wherein the low frequency signal is between approximately 0.1 and 10 Hz.

7. The magnetic depolarizer of claim 1 , further comprising a positioning element in which the at least one magnetic coil and the control circuitry may be disposed and configured to be situated on or adjacent the head of the patient.

8. A method for treating a neurological disorder of a patient through a transcranial magnetic stimulation device, the method comprising:

causing at least one magnetic coil of the transcranial magnetic stimulation device to deliver at least one magnetic pulse to the patient,

wherein the at least one magnetic pulse is provided by a carrier frequency having a low frequency signal modulated thereon.

9. The method of claim 8 , further comprising setting the duration of the at least one magnetic pulse to a duration between about 10 microseconds and 1,000 microseconds.

10. The method of claim 8 , wherein the at least one magnetic pulse has an intensity of 0.1 to 10 Tesla.

11. The method of claim 8 , wherein the carrier frequency is on the order of 100 Hz.

12. The method of claim 8 , wherein the low frequency signal is between approximately 0.1 and 10 Hz.

13. The method of claim 8 , further comprising generating the at least one magnetic pulse in response to activation of the transcranial magnetic stimulation device by the patient.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Jun 4, 2025
From: CRG SERVICING LLC AS SUCCESSOR TO CAPITAL ROYALTY PARTNERS II L.P., CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P., AND PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
To: NEUROPACE INC.
Reel/Frame 071495/0800 →
RELEASE OF SECURITY INTEREST Recorded Oct 29, 2019
From: ORTHOFIX, INC.
To: ENEURA, INC.
Reel/Frame 050859/0403 →
SECURITY INTEREST Recorded Apr 4, 2019
From: NEUROPACE, INC.
To: CRG SERVICING LLC
Reel/Frame 049466/0517 →
SECURITY INTEREST Recorded Mar 4, 2019
From: ENEURA, INC.
To: ORTHOFIX INC.
Reel/Frame 048489/0193 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 24, 2016
From: FISCHELL, DAVID R.; UPTON, ADRIAN R.M.
To: NEUROPACE, INC.
Reel/Frame 039809/0158 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 13, 2016
From: FISCHELL, DAVID R.; UPTON, ADRIAN R.M.
To: NEUROPACE, INC.
Reel/Frame 039671/0790 →
Continuity (6)
Continuation 14688935 · Apr 16, 2015
Continuation 12549303 · Aug 27, 2009
Continuation 11436676 · May 16, 2006
Continuation 10245992 · Sep 17, 2002
Division 09652964 · Aug 31, 2000
Related Publication 20160236004A1 · Aug 18, 2016