IP Library Granted Patent US 9,670,282
Granted Patent B2
US 9,670,282 · App. 15/157,460 · Granted Jun 6, 2017

Compositions and methods for diagnosing and treating an inflammation

Inventors: Nathan Karin (Haifa, IL); Rachel Anunu (Haifa, IL); Gizi Wildbaum (Kiryat Yam, IL); Yaniv Zohar (Kiryat Tiv'on, IL); Nir Netzer (Mazkeret Batia, IL)
Assignee: RAPPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES
C07K16/28A61K39/3955C07K16/2896G01N33/6893A61K2039/505C07K2317/21C07K2317/565C07K2317/567C07K2317/76G01N2333/70596G01N2800/065G01N2800/202
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Quick Facts
Patent No.
US 9,670,282
App. No.
15/157,460
Granted
Jun 6, 2017
Kind
B2
Abstract

A method of treating multiple sclerosis (MS) in a subject in need thereof, the method comprising administering to said subject a therapeutically effective amount of an isolated polypeptide comprising an antigen recognition domain capable of specifically binding a human scavenger receptor, wherein said antigen recognition domain comprises CDR amino acid sequences as set forth in SEQ ID NO: 11, 15, 19, 23, 27 and 31, thereby treating MS in the subject.

Claims (1)

1. A method of treating multiple sclerosis (MS) in a subject in need thereof, the method comprising administering to said subject a therapeutically effective amount of an isolated polypeptide comprising an antigen recognition domain capable of specifically binding a human scavenger receptor, wherein said antigen recognition domain comprises CDR amino acid sequences as set forth in SEQ ID NOs.: 11, 15, 19, 23, 27 and 31.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 28, 2018
From: RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES
To: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Reel/Frame 046493/0824 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 14, 2016
From: KARIN, NATHAN; ANUNU, RACHEL; WILDBAUM, GIZI; ZOHAR, YANIV; NETZER, NIR
To: RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES
Reel/Frame 038901/0390 →
Continuity (5)
Continuation 14828615 · Aug 18, 2015
Continuation 13913587 · Jun 10, 2013
Division 11991711
Continuation In Part 11222745 · Sep 12, 2005
Related Publication 20160280785A1 · Sep 29, 2016