Method to reduce mitral regurgitation by cinching the commissure of the mitral valve

1. A method of repairing a mitral heart valve, the mitral heart valve having posterior and anterior leaflets forming an orifice therebetween, an annulus surrounding the posterior and anterior leaflets, and posterior and anterior commissures where the posterior and anterior leaflets join the annulus, the method comprising:

(a) directing a first guide-wire into the left ventricle, across the mitral valve, into the left atrium, and to a first position on a posterior portion of the annulus between the posterior and anterior commissures;

(b) advancing a first tissue anchor along the first guide-wire to the first position on the posterior portion of the annulus, wherein the first tissue anchor comprises a plurality of discrete flat flexible anchor elements;

(c) securing the first tissue anchor to the first position on the posterior portion of the annulus by partially deploying a portion of the first tissue anchor within the left ventricle such that a first plurality of discrete flat flexible anchor elements are disposed and in contact with one another on a first side of the annulus and then deploying a remainder of the first tissue anchor within the left atrium such that a second plurality of discrete flat flexible anchor elements are disposed and in contact with one another on a second side of the annulus;

(d) directing a second guide-wire into the left atrium, across the mitral valve, into the left atrium, and to a second position on an anterior portion of the annulus between the posterior and anterior commissures;

(e) advancing a second tissue anchor along the second guide-wire to the second position on the anterior portion of the annulus, wherein the second tissue anchor comprises a plurality of discrete flat flexible anchor elements;

(f) securing the second tissue anchor to the position on the anterior portion of the annulus by partially deploying a portion of the second tissue anchor within the left atrium such that a first plurality of discrete flat flexible anchor elements are disposed and in contact with one another on the second side of the annulus and then deploying a remainder of the second tissue anchor within the left ventricle such that a second plurality of discrete flat flexible anchor elements are disposed and in contact with one another on the first side of the annulus;

(g) spanning at least one tensile member between the first and second tissue anchors and across the orifice of the mitral valve; and

(h) applying tension to the at least one tensile member, thereby pulling the posterior portion of the annulus toward the anterior portion of the annulus;

wherein the step (c) of securing the first tissue anchor includes the step of applying tension to a first tensile member and the step (f) of securing the second tissue anchor includes the step of applying the tension to a second tensile member, wherein the first and second tensile members are distinct and separate from one another.

2. The method according to claim 1 , wherein the steps (a)-(h) are performed percutaneously with at least one catheter.

3. The method according to claim 2 , wherein the at least one catheter is percutaneously directed into the right atrium from an artorial access point to an aorta around an aortic arch through an aortic valve and between a pair of chordae tendineae.

4. The method according to claim 1 further comprising:

maintaining the tension applied to the at least one tensile member with a suture locker.

5. The method according to claim 4 , wherein the suture locker includes a locker body and a slidable member coupled to the locker body for securing the at least one tensile member, the slidable member having a latent condition wherein the at least one tensile member is moveable relative to the locker body and an activated condition wherein the at least one tensile member is locked relative to the locker body.

6. The method according to claim 1 , wherein the posterior leaflet includes P1, P2, and P3 regions and the anterior leaflet includes A 1, A2, and A3 regions, the position on the anterior portion of the annulus being near the A1 region and the second position on the posterior portion of the annulus being near the P1 region.

7. The method according to claim 1 , wherein the posterior leaflet includes P1, P2, and P3 regions and the anterior leaflet includes A 1, A2, and A3 regions, the first position on the anterior portion of the annulus being near the A3 region and the second position on the posterior portion of the annulus being near the P3 region.