IP Library Granted Patent US 9,750,581
Granted Patent B2
US 9,750,581 · App. 15/159,598 · Granted Sep 5, 2017

Method for enhancing ultrasound visibility of hyperechoic materials

Inventors: Frederick A. Ahari (Belleair Beach, FL); John S. Fisher (Belleair, FL)
Assignee: Devicor Medical Products, Inc.
A61B90/39A61F2/02A61K49/226A61L31/06A61L31/145A61B2090/3908A61B2090/3925A61B2090/3995
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Quick Facts
Patent No.
US 9,750,581
App. No.
15/159,598
Granted
Sep 5, 2017
Kind
B2
Abstract

A hydrogel plug is placed under stress during its curing stage, in one embodiment, by application of an externally applied force. The stress may also be induced during or after the dehydration process. The direction of the externally applied force increases the length, width, depth, or radial extent of the plug. The elastic limit of the plug is exceeded when the external force is applied so that the plug substantially retains its stressed size and shape when the externally applied force is removed. When the stretched or otherwise deformed dehydrated plug is hydrated, it substantially returns to the configuration it had prior to its dehydration and prior to the application of the externally applied force.

Claims (23)

1. A method for making a hydrogel plug that contracts in a controlled manner when hydrated, comprising:

forming said hydrogel plug so that it has a predetermined geometric configuration when in a repose configuration;

subjecting said hydrogel plug to a dehydration process;

inducing stress into said hydrogel plug during said dehydration process by applying an external force;

controlling said stress so that said hydrogel plug is stretched beyond its elastic limit and assumes and retains a stretched preselected geometrical configuration;

removing said externally applied force during the dehydration process so that the hydrogel plug substantially retains said stretched predetermined geometrical configuration before the dehydration process is concluded; and

curing said dehydrated hydrogel plug;

wherein the cured and dehydrated hydrogel plug, when hydrated, contracts until assuming the in repose configuration, and

wherein curing said dehydrated hydrogel plug comprises curing said dehydrated hydrogel plug inside a core of a coil and between loops of the coil to achieve a selected coverage of a hyperechoic marker.

2. The method of claim 1 , further comprising:

applying said external force to said hydrogel plug during said dehydration process by subjecting said hydrogel plug to a force coincident with a longitudinal axis of said hydrogel plug;

wherein said cured and dehydrated hydrogel plug, when hydrated, contracts only in a longitudinal direction.

3. The method of claim 2 , further comprising:

inducing said stress into said hydrogel plug during said dehydration process by subjecting said hydrogel plug to an externally applied force coincident with a transverse axis of said hydrogel plug, said transverse axis being normal to said longitudinal axis;

wherein said cured and dehydrated hydrogel plug, when hydrated, contracts only in a transverse direction.

4. The method of claim 3 , further comprising:

inducing said stress into said hydrogel plug during said dehydration process by subjecting said hydrogel plug to an externally applied force coincident with an axis normal to said longitudinal axis and normal to said transverse axis of said hydrogel plug;

wherein said cured and dehydrated hydrogel plug, when hydrated, contracts only in a direction normal to said longitudinal axis and normal to said transverse axis.

5. The method of claim 4 , further comprising:

inducing said stress into said hydrogel plug during said dehydration process by subjecting said hydrogel plug to an externally applied radial force, said radial force causing said hydrogel plug to expand radially relative to a longitudinal axis and to contract in length along said longitudinal axis;

determining a radial expansion to longitudinal contraction ratio;

said cured and dehydrated hydrogel plug, when hydrated, contracting in a radial direction relative to said longitudinal axis and contracts in length along said longitudinal axis when hydrated; and

measuring the amount of radial expansion and the amount of longitudinal contraction and dividing the radial expansion by the longitudinal contraction to derive a radial expansion to longitudinal contraction ratio.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 7, 2020
From: BIOPSY SCIENCES, LLC
To: MED-GENESIS, LLC
Reel/Frame 053998/0496 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 20, 2018
From: DEVICOR MEDICAL PRODUCTS, INC.
To: BIOPSY SCIENCES, LLC
Reel/Frame 045289/0549 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 30, 2016
From: MED-GENESIS, LLC
To: DEVICOR MEDICAL PRODUCTS, INC.
Reel/Frame 040809/0672 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 22, 2016
From: AHARI, FREDERICK; FISHER, JOHN S.
To: MED-GENESIS, LLC
Reel/Frame 039835/0331 →
Continuity (3)
Division 13911708 · Jun 6, 2013
Division 11277721 · Mar 28, 2006
Related Publication 20160262846A1 · Sep 15, 2016