IP Library Granted Patent US 10,245,369
Granted Patent B2
US 10,245,369 · App. 15/163,128 · Granted Apr 2, 2019

Systems and methods for priming hemodialysis using dialysis fluid

Inventors: Thomas Kelly (Highland Park, IL); Robert W. Childers (New Port Richey, FL); Don Busby (Thousand Oaks, CA); Rodolfo Roger (Clearwater, FL); Waleed Mutasem El Sayyid (Dover, NJ); Shahid Din (Palm Harbor, FL)
Assignees: Baxter International Inc.; Baxter Healthcare SA
A61M1/3621A61M1/1037A61M1/16A61M1/1601A61M1/166A61M1/1607A61M1/167A61M1/1613A61M1/1621A61M1/1629A61M1/1633A61M1/1635A61M1/1656A61M1/1668A61M1/1672A61M1/1696A61M1/267A61M1/288A61M1/341A61M1/342A61M1/3417A61M1/3427A61M1/3431A61M1/3434A61M1/3437A61M1/3444A61M1/3451A61M1/3458A61M1/3465A61M1/3468A61M1/3472A61M1/3486A61M1/365A61M1/3624A61M1/3626A61M1/3627A61M1/3643A61M1/3644A61M1/3646A61M1/3647A61M1/3649A61M1/3652A61M1/3656A61M1/101A61M1/1006A61M1/1012A61M1/1039A61M1/1062A61M1/1081A61M1/1086A61M2202/0413A61M2205/12A61M2205/13A61M2205/15A61M2205/18A61M2205/276A61M2205/3317A61M2205/3324A61M2205/3327A61M2205/3331A61M2205/3334A61M2205/3337A61M2205/3344A61M2205/3368A61M2205/3379A61M2205/3393A61M2205/3553A61M2205/3561A61M2205/3584A61M2205/502A61M2205/505A61M2205/52A61M2205/75
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,245,369
App. No.
15/163,128
Granted
Apr 2, 2019
Kind
B2
Abstract

A method for priming a hemodialysis treatment includes: providing a disposable cassette including at least a portion of a dialysate circuit and at least a portion of a blood circuit; placing a dialyzer in fluid communication with the dialysate circuit via a to-dialyzer dialysate line and a from-dialyzer dialysate line; placing the dialyzer in fluid communication with the blood circuit via an arterial blood line and a venous blood line; placing a source of dialysis fluid in fluid communication with the dialyzer; priming the dialysate circuit with dialysis fluid from the source while both the to-dialyzer dialysate line and the from-dialyzer dialysate line are connected at their dialyzer ends to the dialyzer; and priming the blood circuit with dialysis fluid from the source by actuating at least one valve provided by the disposable cassette.

Claims (37)

1. A method for priming a hemodialysis treatment comprising:

providing a disposable cassette including at least a portion of a dialysate circuit and at least a portion of a blood circuit;

placing a dialyzer in fluid communication with the dialysate circuit via a to-dialyzer dialysate line and a from-dialyzer dialysate line;

placing the dialyzer in fluid communication with the blood circuit via an arterial blood line and a venous blood line;

placing a source of dialysis fluid in fluid communication with the dialyzer;

priming the dialysate circuit with dialysis fluid from the source while both the to-dialyzer dialysate line and the from-dialyzer dialysate line are connected at their dialyzer ends to the dialyzer; and

priming the blood circuit with dialysis fluid from the source by actuating at least one valve provided by the disposable cassette.

2. The method of claim 1 , wherein priming the blood circuit includes reversing a blood pump at least one time.

3. The method of claim 2 , which includes reversing the blood pump after a drip chamber is filled with fluid.

4. The method of claim 1 , wherein priming the blood circuit includes connecting patient ends of the arterial blood line and the venous blood line together.

5. The method of claim 1 , which includes actuating at least one valve in the blood circuit to prime the blood circuit.

6. The method of claim 1 , wherein priming the blood circuit includes directing the dialysis fluid at one time in a first direction away from the dialyzer and at another time in a second direction towards the dialyzer.

7. The method of claim 1 , wherein priming the blood circuit includes directing the dialysis fluid at one time in a treatment operation direction and at another time in a reverse of the treatment operation direction.

8. The method of claim 1 , wherein priming the blood circuit includes pumping the dialysis fluid through the dialyzer.

9. A dialysis machine configured and arranged to perform the method of claim 1 .

10. A method for priming a hemodialysis treatment comprising:

providing a sorbent cartridge for cleaning used dialysis fluid returning from a dialyzer;

preparing a batch of dialysis fluid in a quantity commensurate with being recycled through the sorbent cartridge multiple times;

priming a dialysate circuit in fluid communication with the dialyzer using the batch of dialysis fluid, while both a to-dialyzer dialysate line and a from-dialyzer dialysate line are connected at their dialyzer ends to the dialyzer; and

priming a blood circuit in fluid communication with the dialyzer using the batch of dialysis fluid.

11. The method of claim 10 , wherein preparing the batch of dialysis fluid includes mixing water and concentrate.

12. The method of claim 10 , wherein priming the blood circuit includes pumping dialysis fluid from the batch of dialysis fluid through the dialyzer.

13. The method of claim 10 , wherein priming the blood circuit includes connecting patient ends of an arterial blood line connected to the blood circuit and a venous blood line connected to the blood circuit together.

14. A dialysis machine configured and arranged to perform the method of claim 10 .

15. A dialysis system comprising:

a dialyzer;

a disposable cassette including at least a portion of a dialysate circuit and at least a portion of a blood circuit, the dialysate circuit in fluid communication with the dialyzer via a to-dialyzer dialysate line and a from-dialyzer dialysate line, the blood circuit in fluid communication with the dialyzer via an arterial blood line and a venous blood line;

a source of dialysis fluid in fluid communication with the dialyzer;

at least one dialysis fluid pump configured to pump dialysis fluid from the source of dialysis fluid through the dialysate circuit;

at least one blood pump configured to pump blood from a patient through the blood circuit; and

at least one processor configured to operate a sequence in which (i) the dialysate circuit is primed with dialysis fluid from the source of dialysis fluid while both the to-dialyzer dialysate line and the from-dialyzer dialysate line are connected at their dialyzer ends to the dialyzer; and

(ii) the blood circuit is primed with dialysis fluid from the source of dialysis fluid by actuating at least one valve provided by the disposable cassette.

16. The dialysis system of claim 15 , wherein the source of dialysis fluid includes regenerated dialysis fluid from a sorbent cartridge.

17. The dialysis system of claim 15 , wherein the at least one processor reverses the at least one blood pump at least one time to prime the blood circuit.

18. The dialysis system of claim 15 , wherein the at least one valve is located in the portion of the blood circuit included in the disposable cassette.

19. The dialysis system of claim 15 , wherein the at least one valve is in fluid communication with the arterial blood line.

20. The dialysis system of claim 15 , wherein the at least one processor is configured to prime the blood circuit with patient ends of the arterial blood line and the venous blood line connected together.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER INTERNATIONAL INC.
To: VANTIVE US HEALTHCARE LLC
Reel/Frame 073413/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER HEALTHCARE SA
To: VANTIVE HEALTH GMBH
Reel/Frame 073438/0790 →
SECURITY INTEREST Recorded Jan 31, 2025
From: VANTIVE US HEALTHCARE LLC; GAMBRO RENAL PRODUCTS, INC.
To: ARES CAPITAL CORPORATION
Reel/Frame 070076/0701 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 25, 2016
From: KELLY, THOMAS; CHILDERS, ROBERT W.; BUSBY, DON; ROGER, RODOLFO; EL SAYYID, WALEED MUTASEM; DIN, SHAHID
To: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE S.A.
Reel/Frame 038715/0310 →
Continuity (5)
Continuation 13749309 · Jan 24, 2013
Continuation 13222622 · Aug 31, 2011
Continuation 10982170 · Nov 4, 2004
Provisional Application 60517730 · Nov 5, 2003
Related Publication 20160263306A1 · Sep 15, 2016
Cited By (5)
US 12,285,553 US 12,329,890 US 12,350,413 US 12,527,898 US 12,558,468