IP Library Granted Patent US 9,668,989
Granted Patent B2
US 9,668,989 · App. 15/168,176 · Granted Jun 6, 2017

Materials and methods for controlling infections

Inventors: Carolyn L. Twomey (Lawrenceville, GA); Gareth Clarke (Lawrenceville, GA); Samuel J. Zaidspiner (Lawrenceville, GA)
Assignee: INNOVATION TECHNOLOGIES, INC.
A61K31/155A61F13/00063A61K9/0019A61K9/0043A61K9/0073A61K9/0085A61K9/08A61K31/191A61K45/06A61L15/44A61L17/005A61L27/54A61L29/08A61L29/16A61L31/08A61L31/16A61M25/0017A61L2300/206
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Quick Facts
Patent No.
US 9,668,989
App. No.
15/168,176
Granted
Jun 6, 2017
Kind
B2
Abstract

The subject invention provides materials methods for reducing infections in subjects. The materials methods utilize chlorhexidine, which has been found to be surprisingly non-toxic. The lack of toxicity facilitates the use of chlorhexidine in contexts that were not previously thought to be possible.

Claims (5)

1. A method for treating a biofilm infection at a site in a subject, wherein said method comprises administering, to the biofilm, an aqueous solution having an active ingredient that consists of chlorhexidine at a concentration of 0.05% or less, wherein the site is an indwelling medical device.

2. The method of claim 1 , wherein the chlorhexidine is chlorhexidine gluconate.

3. The method, according to claim 1 , wherein the indwelling medical device is an implant, stent, or catheter.

4. The method of claim 1 , wherein biofilm is determined to exist at the site prior to the administration of the chlorhexidine.

5. The method, according to claim 1 , wherein the subject is a human.

Assignments (2)
SECURITY INTEREST Recorded Aug 21, 2024
From: INNOVATION TECHNOLOGIES, INC.
To: OXFORD FINANCE LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT
Reel/Frame 068360/0957 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 14, 2016
From: TWOMEY, CAROLYN L.; CLARKE, GARETH; ZAIDSPINER, SAMUEL J.
To: INNOVATION TECHNOLOGIES, INC.
Reel/Frame 038903/0406 →
Continuity (3)
Continuation 14568925 · Dec 12, 2014
Provisional Application 61915281 · Dec 12, 2013
Related Publication 20160271079A1 · Sep 22, 2016