METHODS, SYSTEMS AND DEVICES FOR TREATING ORTHOSTATIC INTOLERANCE
Provided is a method of treating orthostatic intolerance in a patient. The method comprises selecting a patient suffering from orthostatic intolerance and creating a flow pathway between a first vascular location and a second vascular location. The first vascular location comprises a source of arterial blood and the second vascular location comprises a source of venous blood. Systems and devices for creating a flow pathway are also provided.
1 . A method of treating orthostatic intolerance in a patient, comprising:
selecting a patient exhibiting orthostatic intolerance; and
creating a flow pathway between a first vascular location and a second vascular location;
wherein the first vascular location comprises a source of arterial blood;
wherein the second vascular location comprises a source of venous blood; and
wherein the method is constructed and arranged to treat orthostatic intolerance.
2 .- 164 . (canceled)
165 . The method according to claim 1 , wherein the method is constructed and arranged to treat a disease or disorder selected from the group consisting of: orthostatic hypotension; orthostatic hypotension with hypertension; postural orthostatic tachycardia syndrome; and combinations thereof.
166 . The method according to claim 1 , wherein the method is further constructed and arranged to increase the flow of blood to the right side of the heart.
167 . The method according to claim 166 , wherein the increased flow of blood to the right side of the heart increases cardiac output.
168 . The method according to claim 1 , wherein the method is further constructed and arranged to increase cardiac output.
169 . The method according to claim 1 , wherein the method is further constructed and arranged to reduce arterial hypertension.
170 . The method according to claim 1 , wherein the method is further constructed and arranged to treat a patient disease or disorder selected from the group consisting of: hypertension; arterial hypertension; chronic obstructive pulmonary disease; congestive heart failure; lung fibrosis; adult respiratory distress syndrome; lymphangioleiomyomatosis; pulmonary hypertension; sleep apnea; sleep apnea due to hypoxemia; sleep apnea due to hypertension; and combinations thereof.
171 . The method according to claim 1 , wherein the method is further constructed and arranged to cause a physiologic change in the patient selected from the group consisting of: increased oxygen delivery by the arterial system; increased blood volume; increased proportion of blood flow to the descending aorta; increased blood flow to the kidneys; increased blood flow outside the kidneys; increased cardiac output; and combinations thereof.
172 . The method according to claim 1 , wherein creating the flow pathway comprises a procedure selected from the group consisting of: dilating tissue proximate the flow pathway with a balloon; applying energy to tissue proximate the flow pathway such as RF energy applied to tissue; and combinations thereof.
173 . The method according to claim 1 , wherein the flow pathway comprises a flow rate of at least 400 ml/min.
174 . The method according to claim 1 , wherein the first vascular location comprises an artery selected from the group consisting of: aorta; axillary; brachial; ulnar; radial; profundal; femoral; iliac; popliteal; and carotid.
175 . The method according to claim 174 , wherein the second vascular location comprises a vein.
176 . The method according to claim 1 , wherein the second vascular location comprises a vein selected from the group consisting of: inferior vena cava; saphenous; femoral; iliac; popliteal; brachial; basilic; cephalic; medial forearm; medial cubital; axillary; and jugular.
177 . The method according to claim 176 , wherein the first vascular location comprises an artery.
178 . The method according to claim 1 , wherein the first vascular location comprises a chamber of the heart.
179 . The method according to claim 1 , wherein the flow pathway comprises a diameter of at least 2.5 mm.
180 . The method according to claim 179 , wherein the flow pathway comprises a diameter of at least 3.0 mm.
181 . The method according to claim 179 , wherein the flow pathway comprises a diameter of less than or equal to 6.0 mm.
182 . The method according to claim 181 , wherein the flow pathway comprises a diameter of less than 5.0 mm.
183 . The method according to claim 1 , further comprising placing an implant proximate the flow pathway.
184 . The method according to claim 183 , wherein the implant comprises a component selected from the group consisting of: anastomotic clip; suture; staple; adhesive; and combinations thereof.