Methods and devices for deploying and releasing a temporary implant within the body
View Patent ↗Methods, devices and systems for delivering a device assembly into a gastric or other space within the body, allowing the device to expand to occupy volume within the gastric space and, after an effective period of time, delivering a substance or stimulus to begin breakdown of the expanded device so that it may release from the body.
1. A device for temporarily occupying a space within a patient's body, the device comprising:
a device assembly comprising a reservoir, the device assembly having a deployment profile and an active profile, where the deployment profile is smaller than the active profile and permits deployment of the device assembly within a space in the patient's body, where delivery of a fluid into the reservoir causes expansion of the device assembly towards the active profile;
where an extension of the device assembly that extends into the reservoir to form a release channel where the extension forms an elongate structure extending beyond an internal seam of the device assembly;
a release material located within the reservoir and coupled to the release channel while spaced from the internal seam to prevent fluid flow therethrough; and
wherein exposure of the release material to the fluid reduces a structural integrity of the release material, such that degrading of the release material allows fluid flow through the release channel permitting fluid to exit the reservoir.
2. The device of claim 1 , wherein a portion of the extension of the device assembly extending into the reservoir separates the release material from the release channel such that the release material remains entirely physically separated from an environment within the patient's body until reduction of the structural integrity of the release material allows fluid flow through the release channel.
3. The device of claim 1 , further comprising an energy storage element located within the release channel that expands reduction of the structural integrity of the release material.
4. The device of claim 1 , where the extension of the device assembly extending into the reservoir comprises a material that is attached to an exterior surface of the device assembly.
5. The device of claim 1 , where the extension of the device assembly extending into the reservoir comprises an exterior surface of the device assembly.
6. The device of claim 1 , where an exterior surface of the device assembly is fluid impermeable.
7. The device of claim 1 , where the release material comprises a structure selected from the group consisting of a suture, staple, filament, clip, band, and cap.
8. The device of claim 1 , where the release material comprises a mechanical closure.
9. The device of claim 1 , where in the deployment profile, the device assembly is configured to fit within an oral dosage form selected from a group consisting of a pill, capsule, and sleeve.
10. The device of claim 1 , where in the active profile the device assembly comprises an oblate spheroid shape.
11. The device of claim 1 , further comprising a conduit extending from an exterior of the device assembly through a valve and into the reservoir, where the conduit permits delivery of the fluid into the reservoir allowing the device assembly to assume the active profile, wherein the conduit is slidably detachable from the valve such that removal of the conduit causes the valve to seal and prevent the fluid from escaping from the reservoir through the valve.
12. The device of claim 11 , where the conduit remains within an interior of the valve when positioned within the reservoir.
13. The device of claim 1 , where the release material is located on a surface of the device assembly.
14. The device of claim 1 , further comprising an expandable material located within the reservoir.
15. The device of claim 1 , where a volume of the device assembly is at least 300ml in the active profile.
16. The device of claim 11 , where the valve extends beyond an exterior surface of the device assembly.
17. The device of claim 1 , further comprising a swellable filler material in the reservoir.
18. The device of claim 1 , where the device assembly can be reduced to at least a 5ml volume when in the deployment profile.
19. The device of claim 11 , where the conduit extends beyond the valve into the reservoir.
20. The device of claim 1 , where the extension extends from the internal seam of the device assembly towards a center of the reservoir.
21. The device of claim 1 , where the extension extends from an interior wall of the device assembly towards a center of the reservoir.
22. The device of claim 1 , where the release material is spaced from an interior wall of the device assembly.