IP Library Granted Patent US 10,413,300
Granted Patent B2
US 10,413,300 · App. 15/182,453 · Granted Sep 17, 2019

Collateral flow channel sealant delivery methods and systems

Inventors: Sri Radhakrishnan (Cupertino, CA); Ryan Olivera (Granite Bay, CA)
Assignee: Pulmonx Corporation
A61B17/12104A61B5/08A61B5/4848A61B17/1204A61B17/12136A61M16/042A61M16/0406A61M16/0459A61M25/0147A61M25/10A61F2002/043A61F2250/0067A61M2025/0001A61M2202/0413A61M2202/0468A61M2205/502
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Quick Facts
Patent No.
US 10,413,300
App. No.
15/182,453
Granted
Sep 17, 2019
Kind
B2
Abstract

Devices, methods, and systems are provided for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment. A video-assisted thoracoscopic device is inserted into a thoracic cavity of a patient and positioned at a fissure between a target lung compartment and an adjacent lung compartment. A collateral flow channel between the target lung compartment and the adjacent lung compartment is then identified using the video-assisted thoracoscopic device and an agent is injected into the collateral flow channel, thereby reducing the collateral flow channel.

Claims (29)

1. A method for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment, said method comprising:

inserting a video-assisted thoracoscopic device into a thoracic cavity of a patient;

positioning the video-assisted thoracoscopic device at a fissure between a target lung compartment and an adjacent lung compartment;

identifying a collateral flow channel between the target lung compartment and the adjacent lung compartment using the video-assisted thoracoscopic device;

inserting a needle into the thoracic cavity and through tissue forming the collateral flow channel; and

injecting an agent through the needle and into the collateral flow channel, thereby reducing the collateral flow channel.

2. The method of claim 1 , further comprising placing a clip on the collateral channel thereby pinching closed the collateral channel.

3. The method of claim 2 , wherein the clip is a normally closed clip.

4. The method of claim 1 , further comprising cutting tissue at the collateral flow channel thereby disrupting the collateral flow channel.

5. The method of claim 1 , wherein the collateral flow channel is sealed.

6. The method of claim 1 , wherein the agent is a sealant.

7. The method of claim 1 , wherein the agent is a sclerosing agent.

8. The method of claim 1 , wherein the agent is autologous blood.

9. A method as in claim 1 , further comprising:

accessing the target lung compartment using an endobronchial isolation catheter;

isolating the target lung compartment using the endobronchial isolation catheter;

measuring pressure or flow within the target lung compartment; and

verifying the collateral flow channel has been sealed based on the measured pressure or flow.

10. A method as in claim 1 , further comprising placing an endobronchial valve within an airway leading to the target lung compartment.

11. A method as in claim 10 , wherein the endobronchial valve is a one-way flow control valve configured to allow air to flow out of the target lung compartment and prevent air flow into the target lung compartment.

12. A method for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment, said method comprising:

inserting a video-assisted thoracoscopic device into a thoracic cavity of a patient;

positioning the video-assisted thoracoscopic device at a fissure between a target lung compartment and an adjacent lung compartment;

identifying a collateral flow channel between the target lung compartment and the adjacent lung compartment using the video-assisted thoracoscopic device;

placing a clip into the thoracic cavity and on the collateral channel thereby pinching closed the collateral channel.

13. A method for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment, said method comprising:

inserting a video-assisted thoracoscopic device into a thoracic cavity of a patient;

positioning the video-assisted thoracoscopic device at a fissure between a target lung compartment and an adjacent lung compartment; identifying a collateral flow channel between the target lung compartment and the adjacent lung compartment using the video-assisted thoracoscopic device;

cutting tissue at the collateral flow channel from the thoracic cavity thereby disrupting the collateral flow channel.

Assignments (9)
RELEASE OF SECURITY INTEREST Recorded Mar 4, 2026
From: CANADIAN IMPERIAL BANK OF COMMERCE
To: PULMONX CORPORATION
Reel/Frame 075028/0274 →
SECURITY INTEREST Recorded Mar 2, 2026
From: PULMONX CORPORATION
To: PERCEPTIVE CREDIT HOLDINGS V, LP, AS ADMINISTRATIVE AGENT
Reel/Frame 075012/0453 →
SECURITY INTEREST Recorded Jan 27, 2026
From: PULMONX CORPORATION
To: CANADIAN IMPERIAL BANK OF COMMERCE
Reel/Frame 074570/0001 →
RELEASE OF SECURITY INTEREST Recorded Sep 30, 2020
From: OXFORD FINANCE LLC, AS COLLATERAL AGENT
To: PULMONX CORPORATION
Reel/Frame 053952/0044 →
RELEASE OF SECURITY INTEREST Recorded Sep 30, 2020
From: BOSTON SCIENTIFIC CORPORATION
To: PULMONX CORPORATION
Reel/Frame 053953/0548 →
SECURITY INTEREST Recorded Mar 2, 2020
From: PULMONX CORPORATION
To: CANADIAN IMPERIAL BANK OF COMMERCE
Reel/Frame 052916/0213 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 5, 2019
From: RADHAKRISHNAN, SRI; OLIVERA, RYAN
To: PULMONX CORPORATION
Reel/Frame 051193/0648 →
SECURITY INTEREST Recorded Jul 26, 2017
From: PULMONX CORPORATION
To: BOSTON SCIENTIFIC CORPORATION
Reel/Frame 043349/0725 →
SECURITY INTEREST Recorded May 15, 2017
From: PULMONX CORPORATION
To: OXFORD FINANCE LLC, AS COLLATERAL AGENT
Reel/Frame 042466/0349 →
Continuity (2)
Provisional Application 62183170 · Jun 22, 2015
Related Publication 20160367259A1 · Dec 22, 2016
Cited By (1)
US 12,310,594