IP Library Granted Patent US 9,988,610
Granted Patent B2
US 9,988,610 · App. 15/182,778 · Granted Jun 5, 2018

Modified glucosyltransferases for producing branched alpha-glucan polymers

Inventors: Mark S Payne (Wilmington, DE); Yefim Brun (Wilmington, DE); Richard R Bott (Burlingame, CA)
Assignee: E I DU PONT DE NEMOURS AND COMPANY
C12N9/1051C08B37/0009C12N15/102C12P19/04C12P19/18C12Q1/48C12Y204/01027
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Quick Facts
Patent No.
US 9,988,610
App. No.
15/182,778
Granted
Jun 5, 2018
Kind
B2
Abstract

Glucosyltransferase enzymes are disclosed herein that produce branched alpha-glucan polymer. Also disclosed, for example, are polynucleotides encoding these enzymes, as well as methods of producing branched alpha-glucan polymer.

Claims (13)

1. A glucosyltransferase enzyme comprising an amino acid sequence that is at least 97% identical to

SEQ ID NO:87,

SEQ ID NO:91,

SEQ ID NO:95, or

SEQ ID NO:97,

wherein said glucosyltransferase enzyme lacks

the amino acid sequence of SEQ ID NO:79, and

wherein said glucosyltransferase enzyme produces a branched alpha-glucan polymer.

2. A reaction solution comprising water, sucrose, and a glucosyltransferase enzyme according to claim 1 .

3. A method for producing a branched alpha-glucan polymer comprising:

(a) contacting at least water, sucrose, and a glucosyltransferase enzyme according to claim 1 , whereby branched alpha-glucan polymer is produced, and

b) optionally, isolating the branched alpha-glucan polymer produced in step (a).

4. The glucosyltransferase of claim 1 , wherein the glucosyltransferase comprises an amino acid sequence that is at least 98% identical to SEQ ID NO:87, SEQ ID NO:91, SEQ ID NO:95, or SEQ ID NO:97.

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 28, 2020
From: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
To: NUTRITION & BIOSCIENCES USA 4, INC.
Reel/Frame 055028/0496 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ENTITY TYPE PREVIOUSLY RECORDED AT REEL: 049879 FRAME: 0043. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Sep 6, 2019
From: E. I. DU PONT DE NEMOURS AND COMPANY
To: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
Reel/Frame 050300/0408 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 26, 2019
From: E. I. DU PONT DE NEMOURS AND COMPANY
To: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
Reel/Frame 049879/0043 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2017
From: DANISCO US INC.
To: E. I. DU PONT DE NEMOURS AND COMPANY
Reel/Frame 041394/0326 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 27, 2017
From: BOTT, RICHARD R
To: DANISCO US INC.
Reel/Frame 041102/0399 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 23, 2017
From: PAYNE, MARK S; BRUN, YEFIM
To: E. I. DUPONT DE NEMOURS AND COMPANY
Reel/Frame 041048/0799 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 11, 2017
From: PAYNE, MARK S; BRUN, YEFIM; BOTT, RICHARD R
To: E. I. DUPONT DE NEMOURS AND COMPANY
Reel/Frame 040946/0001 →
Continuity (3)
Provisional Application 62180788 · Jun 17, 2015
Provisional Application 62180779 · Jun 17, 2015
Related Publication 20170002336A1 · Jan 5, 2017