IP Library Granted Patent US 10,512,405
Granted Patent B2
US 10,512,405 · App. 15/201,456 · Granted Dec 24, 2019

Method and system for monitoring hemodynamics

Inventors: Baruch Levy (Lehavim, IL); Eliezer Schusman (RaAnana, IL); Omri Sarfati (Moshav Mishmeret, IL); Mordechai Dinur (Karney Shomron, IL)
Assignee: Cheetah Medical, Inc.
A61B5/0205A61B5/026A61B5/029A61B5/02028A61B5/0402A61B5/0452A61B5/053A61B5/14535A61B5/412A61B5/4818A61B5/7228A61B8/065A61B5/024A61B5/02007A61B5/4836A61B5/4875A61B5/7239
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,512,405
App. No.
15/201,456
Granted
Dec 24, 2019
Kind
B2
Abstract

A system for monitoring hemodynamics of a subject is disclosed. The system comprises: a signal generating system configured for providing at least an output electric signal and transmitting the output signal to an organ of the subject. The system also comprises a demodulation system configured for receiving an input electrical signal sensed from the organ responsively to the output electric signal, and for modulating the input signal using the output signal to provide an in-phase component and a quadrature component of the input signal. The system also comprises a processing system configured for monitoring the hemodynamics based on the in-phase and the quadrature components.

Claims (33)

1. A system for monitoring hemodynamics of a subject, comprising:

medical leads connectable to an organ at a first part of the body of the subject, and to an organ at a second part of the body of the subject;

a signal generating system configured for providing at least a first output electric signal and a second output electric signal, and transmitting, via said medical leads, said first output signal to said organ at said first part of the body of the subject and said second output signal to said organ at said second part of the body of the subject;

a demodulation system configured for receiving via said medical leads a first input electrical signal sensed from said first part of the body and a second input electrical signal sensed from said second part of the body, and for demodulating each input electrical signal to provide an in-phase component and a quadrature component of each input signal;

a signal processing system having a circuit for generating a linear combination of powers of a respective in-phase component and a respective quadrature component of each input signal, to respectively provide a first hybrid signal and a second hybrid signal, and for generating on a display device a graphical output co-displaying said hybrid signals.

2. The system according to claim 1 , wherein said first part of the body is a right part of the body and said second part of the body is a left part of the body.

3. The system according to claim 2 , wherein the right part of the body is a right part of the thorax, and the left part of the body is a left part of the thorax.

4. The system according to claim 1 , wherein said first and said second output electric signals are independent from each other.

5. The system according to claim 1 , wherein said first and said second output electric signals are mutually dependent signals.

6. The system according to claim 1 , wherein said processing system is configured to determine, based on at least one of said hybrid signals, at least one property selected from the group consisting of stroke volume (SV), cardiac output (CO), ventricular ejection time (VET), cardiac index (CI), thoracic fluid content (TFC), total peripheral resistance index (TPRI), blood vessel compliance.

7. The system according to claim 1 , wherein said processing system is configured to estimate exercise capacity of the subject based on at least one of said hybrid signals.

8. The system according to claim 1 , wherein processing system is configured to identify sleep apnea events based on at least one of said hybrid signals.

9. The system according to claim 1 , wherein processing system is configured to assess the likelihood that the subject develops sepsis based on at least one of said hybrid signals.

10. The system according to claim 1 , wherein processing system is configured to predict onset of electromechanical dissociation based on at least one of said hybrid signals.

11. The system according to claim 1 , wherein processing system is configured to assess blood hematocrit based on at least one of said hybrid signals.

12. A method of monitoring hemodynamics of a subject, comprising:

generating at least a first output electric signal and a second output electric signal;

by medical leads, transmitting said first output signal to an organ at a first part of the body of the subject and said second output signal to an organ at a second part of the body of the subject;

by medical leads, receiving a first input electrical signal sensed from said first part of the body and a second input electrical signal sensed from said second part of the body,

modulating each input electrical signal to provide an in-phase component and a quadrature component of each input signal;

combining a respective in-phase component and a respective quadrature component of each input signal, to respectively provide a first hybrid signal and a second hybrid signal, and

generating on a display device a graphical output co-displaying said hybrid signals;

wherein at least one of said hybrid signals comprises a linear combination of powers of a respective in-phase component and a respective quadrature component of a respective input electrical signal.

13. The method according to claim 12 , wherein said first part of the body is a right part of the body and said second part of the body is a left part of the body.

14. The method according to claim 13 , wherein the right part of the body is a right part of the thorax, and the left part of the body is a left part of the thorax.

15. The method according to claim 12 , wherein said first and said second output electric signals are independent from each other.

16. The method according to claim 12 , wherein said first and said second output electric signals are mutually dependent signals.

17. The method according to claim 12 , comprising determining based on at least one of said hybrid signals, at least one property selected from the group consisting of stroke volume (SV), cardiac output (CO), ventricular ejection time (VET), cardiac index (CI), thoracic fluid content (TFC), total peripheral resistance index (TPRI), blood vessel compliance.

18. The method according to claim 12 , comprising estimating exercise capacity of the subject based on at least one of said hybrid signals.

19. The method according to claim 12 , comprising identifying sleep apnea events based on at least one of said hybrid signals.

20. The method according to claim 12 , comprising diagnosing the subject with sepsis based on at least one of said hybrid signals.

21. The method according to claim 12 , comprising predicting onset of electromechanical dissociation based on at least one of said hybrid signals.

22. The method according to claim 12 , comprising determining blood hematocrit based on at least one of said hybrid signals.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2020
From: CHEETAH MEDICAL, INC.
To: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE SA
Reel/Frame 053268/0682 →
SECURITY INTEREST Recorded Jan 16, 2019
From: CHEETAH MEDICAL, INC.
To: SWK FUNDING LLC, AS AGENT
Reel/Frame 048033/0287 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 5, 2016
From: LEVY, BARUCH; SCHUSMAN, ELIEZER; SARFATI, OMRI; DINUR, MORDECHAI
To: CHEETAH MEDICAL, INC.
Reel/Frame 040229/0392 →