IP Library Patent Application 15204693
Patent Application
App. No. 15/204,693

METHODS FOR DIAGNOSING, PROGNOSING, OR THERANOSING A CONDITION USING RARE CELLS

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Quick Facts
Patent No.
US None
App. No.
15/204,693
Abstract

Described herein are methods for diagnosing, prognosing, or theranosing a condition using rare cells.

Claims (11)

1 .- 10 . (canceled)

11 . A method for diagnosing, theranosing, or prognosing a condition in a patient comprising:

performing one or more nucleic acid analysis on a first sample obtained from said patient; enumerating one or more rare cells in a second sample from said patient; and diagnosing, theranosing, or prognosing the condition in said patient based on said enumerating one or more rare cells and said performing one or more nucleic acid analysis.

12 . The method of claim 11 , wherein the first sample is a biopsy sample, the second sample is a blood sample, or the first and second sample are the same sample.

13 . The method of claim 11 , wherein performing one or more nucleic acid analysis comprises SNP analysis, mRNA analysis, or sequencing.

14 . The method of claim 11 , wherein the one or more rare cells comprise circulating tumor cells.

15 . The method of claim 11 , wherein the one or more rare cells are enriched using a microfluidic device.

16 . The method of claim 15 , wherein the microfluidic device comprises one or more binding moieties and/or an array of obstacles.

17 . The method of claim 16 , wherein the one or more binding moieties comprise anti-EpCAM.

18 . The method of claim 11 , further comprising subjecting said patient to one or more therapeutic treatments; repeating said performing one or more nucleic acid analysis and said enumerating one or more rare cells; and diagnosing, prognosing or theranosing the condition in the patient.

19 .- 37 . (canceled)

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 17, 2017
From: KOPF-SILL, ANNE R; WU, LENA; STOUGHTON, ROLAND
To: ON-Q-ITY, INC.
Reel/Frame 041621/0235 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 17, 2017
From: ON-Q-ITY, INC.
To: GPB SCIENTIFIC, LLC
Reel/Frame 041621/0254 →