IP Library Patent Application 15208591
Patent Application
App. No. 15/208,591

SOLID DRESSING FOR TREATING WOUNDED TISSUE

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Quick Facts
Patent No.
US None
App. No.
15/208,591
Abstract

Disclosed are solid dressings for treated wounded tissue in mammalian patients, such as a human, comprising a haemostatic layer consisting essentially of fibrinogen and a fibrinogen activator, wherein the fibrinogen is present in an amount between 3.0 mg/cm 2 of the wound facing surface of the dressing and 13.0 mg/cm 2 of the wound facing surface of the dressing. Also disclosed are methods for treating wounded tissue.

Claims (22)

1 . A solid dressing for treating wounded tissue in a mammal comprising at least one haemostatic layer consisting essentially of fibrinogen and a solvent consisting of water and a fibrinogen activator wherein said haemostatic layer is substantially homogeneous, wherein said fibrinogen is present in an amount about 13.0 mg/cm 2 of the wound facing surface of said dressing, and wherein the moisture content of said solid dressing is from 6% to 44%.

2 . The solid dressing of claim 1 , further comprising at least one support layer.

3 . The solid dressing of claim 2 , wherein said support layer comprises a backing material.

4 . The solid dressing of claim 2 , wherein said support layer comprises an internal support material.

5 . The solid dressing of claim 2 ; wherein said support layer comprises a resorbable material.

6 . The solid dressing of claim 2 , wherein said support layer comprises a non resorbable material.

7 . (canceled)

8 . The solid dressing of claim 3 , further comprising at least physiologically acceptable adhesive between said haemostatic layer and said backing layer.

9 - 11 . (canceled)

12 . The solid dressing of claim 1 , wherein said haemostatic layer also contains a fibrin crosslinker and/or a source of calcium ions.

13 . The solid dressing of claim 1 , wherein said haemostatic layer also contains one or more of the following: at least one filler, at least one solubilizing agent, at least one foaming agent and at least one release agent.

14 - 21 . (canceled)

22 . The solid dressing of claim 1 , wherein said haemostatic layer is composed of a plurality of particles, each of said particles consisting essentially of fibrinogen and thrombin.

23 . The solid dressing of claim 22 , wherein said haemostatic layer further contains at least one binding agent in an amount effective to improve the adherence of said particles to one another.

24 . (canceled)

25 . The solid dressing of claim 1 , wherein said haemostatic layer is a monolith.

26 . The solid dressing of claim 1 , wherein said haemostatic layer has been lyophilized.

27 - 37 . (canceled)

38 . The solid dressing of claim 1 , wherein said fibrinogen activator is present in an amount between 2.50 Units/mg of fibrinogen component and 0.025 Units/mg of the fibrinogen.

39 . (canceled)

40 . A method of treating wounded tissue in a mammal, comprising placing a solid dressing of claim 1 to said wounded tissue and applying sufficient pressure to said dressing for a sufficient time for enough fibrin to form to reduce the loss of blood and/or other fluid from said wounded tissue.

41 . The solid dressing of claim 1 , wherein said moisture content is at least 28%.

Assignments (3)
COURT ORDER Recorded Mar 20, 2017
From: STB, LTD.
To: RESOURCE TRANSITION CONSULTANTS, LLC
Reel/Frame 041653/0001 →
SECURITY INTEREST Recorded Jul 13, 2016
From: STB, LTD.
To: HDG LP
Reel/Frame 039148/0612 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 13, 2016
From: MACPHEE, MARTIN; BEALL, DAWSON
To: STB, LTD.
Reel/Frame 039149/0250 →