BIOABSORBABLE POLYMERIC MEDICAL DEVICE
In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend.
1 . A flexible scaffold formed from expansion-crystallizable bioabsorbable polymer material comprising:
a first sinusoidal strut pattern comprising a series of sinusoids;
a nested hoop structure; and
a second sinusoidal strut pattern comprising a series of, said sinusoids of said second sinusoidal strut pattern being shifted from about 0° to about 180° with respect to said sinusoids of said first sinusoidal strut pattern; and
when fully expanded, the first and second sinusoidal strut patterns maintain a sinusoidal shape and the nested hoop structure forms a hoop structure.
2 . The scaffold of claim 1 , wherein said first sinusoidal strut pattern and said second sinusoidal strut pattern are repeated multiple times, one after the other to form the scaffold.
3 . The scaffold of claim 1 , wherein said first sinusoidal strut pattern and said second sinusoidal strut pattern are the same.
4 . The scaffold of claim 1 , wherein said first sinusoidal strut pattern and said second sinusoidal strut pattern are different.
5 . The scaffold of claim 1 , wherein said second sinusoidal strut pattern is connected to said first sinusoidal strut pattern at at least two points.
6 . The scaffold of claim 1 , wherein said second sinusoidal strut pattern is connected to said first sinusoidal strut pattern at at least three points.
7 . The scaffold of claim 1 , wherein said bioabsorbable polymer comprises a poly-lactide polymer.
8 . The scaffold of claim 1 , wherein said bioabsorbable polymer comprises a base polymer comprising a poly L-lactide moiety, and/or a poly D-lactide moiety, and/or a poly L-lactide-co-PEG moiety, and/or a poly D-lactide-co-PEG moiety, linked with a modifying copolymer thereof, wherein the modifying copolymer comprises poly L(or D)-lactide-co-tri-methylene-carbonate or poly L(or D)-lactide-co-ε-caprolactone.
9 . The scaffold of claim 1 , wherein the nested hoop structure is located between said first and said second sinusoidal strut patterns.
10 . A biosorbable and flexible scaffold formed from expansion-crystallizable bioabsorbable polymer material comprising:
a first sinusoidal strut pattern comprising a series of sinusoids;
a nested hoop structure; and
a second sinusoidal strut pattern comprising a series of sinusoids, said sinusoids of said second sinusoidal strut pattern being in phase with respect to said sinusoids of said first sinusoidal strut pattern.
11 . The scaffold of claim 10 , wherein said first sinusoidal strut pattern and said second sinusoidal strut pattern are repeated multiple times, one after the other to form the scaffold.
12 . The scaffold of claim 10 , wherein said first sinusoidal strut pattern and said second sinusoidal strut pattern are the same.
13 . The scaffold of claim 10 , wherein said first sinusoidal strut pattern and said second sinusoidal strut pattern are different.
14 . The scaffold of claim 10 , wherein said second sinusoidal strut pattern is connected to said first sinusoidal strut pattern at at least two points.
15 . The scaffold of claim 10 wherein said second sinusoidal strut pattern is connected to said first sinusoidal strut pattern at at least three points.
16 . The scaffold of claim 10 wherein said bioabsorbable polymer is a poly-lactide polymer.
17 . The scaffold of claim 10 , wherein said bioabsorbable polymer comprises a base polymer comprising a poly L-lactide moiety, and/or a poly D-lactide moiety, and/or a poly L-lactide-co-PEG moiety, and/or a poly D-lactide-co-PEG moiety, linked with a modifying copolymer thereof, wherein the modifying copolymer comprises poly L(or D)-lactide-co-tri-methylene-carbonate or poly L(or D)-lactide-co-ε-caprolactone.