Liquid stylet apparatus

1. A liquid stylet comprising:

a tube with a transparent portion and at least partially filled with a liquid;

a powering device in fluid communication with the tube;

a catheter located distally of the tube and attached in fluid communication with the tube, wherein the catheter is at least partially filled with the liquid;

a collection device located distally of the catheter and attached in fluid communication with the catheter, wherein the collection device is configured to engage a target area of a patient; and

an indicator contacting the liquid and located at least partially within the tube, wherein a position of the indicator within the tube is visible through the transparent portion,

wherein the indicator is fixed relative to liquid located immediately proximally and liquid located immediately distally of the indicator such that the indicator moves proximally when the surrounding liquid moves proximally due to tissue collection at the collection device.

2. The liquid stylet apparatus of claim 1 , the liquid stylet apparatus further comprising a valve that controls flow of the liquid between the tube and the catheter.

3. The liquid stylet apparatus of claim 2 , wherein the valve comprises a valve member with a channel, and wherein the liquid stylet apparatus further comprises:

a first state wherein fluid communication between the tube and the catheter is provided through the channel; and

a second state wherein the valve member seals the tube from the catheter, thereby preventing fluid communication through the channel.

4. The liquid stylet apparatus of claim 3 , wherein the channel is in fluid communication with a vacuum chamber in the second state.

5. The liquid stylet apparatus of claim 4 , wherein the channel is in fluid communication with outside air in the second state.

6. The liquid stylet apparatus of claim 4 , further comprising a third state wherein the tube is in fluid communication with the catheter through the channel, and wherein the indicator comprises an air bubble.

7. The liquid stylet apparatus of claim 1 , further comprising graduations aligned with and providing a visual indication of the position of the indicator corresponding with a position of the liquid in a distal end of the collection device.

8. The liquid stylet apparatus of claim 1 , wherein the powering device operates to form a vacuum for drawing the liquid into the tube.

9. A liquid stylet apparatus comprising:

a tube, wherein the tube is filled with a liquid, the liquid comprising a saline solution pre-filled within the tube;

an indicator located at least partially within the tube, wherein the indicator is fixed relative to liquid located immediately proximally and liquid located immediately distally of the indicator such that the indicator moves proximally when the surrounding liquid moves proximally due to tissue collection at a collection device;

a catheter located distally of, and in fluid communication with, the tube and at least partially filled with the liquid;

the collection device, wherein the collection device is located at a distal end of the liquid stylet apparatus and in fluid communication with the catheter, wherein the collection device is configured to engage and draw a tissue sample from a patient; and

a powering device located proximally of the tube, the powering device actuatably providing vacuum for drawing the liquid from the catheter to the tube.

10. The liquid stylet apparatus of claim 9 , wherein the collection device comprises a needle with a needle lumen extending therethrough, said needle lumen continuous with and providing fluid communication with the tube and the catheter.

11. The liquid stylet apparatus of claim 10 , wherein the collection device further comprises a piston, the piston being slidable within the needle lumen, and the piston being configured to provide a seal between the liquid and the tissue sample.

12. The liquid stylet apparatus of claim 9 , further comprising a first valve located proximally of the tube and second valve located distally of the tube.

13. The liquid stylet apparatus of claim 12 , wherein the first valve controls fluid communication between the tube and the vacuum.

14. The liquid stylet apparatus of claim 12 , wherein the second valve controls fluid communication between the tube and the catheter.

15. The liquid stylet apparatus of claim 9 , wherein the powering device comprises a first piston located within a syringe body and coupled to a plunger, wherein the first piston is slidable within the syringe body.

16. The liquid stylet apparatus of claim 9 , wherein the liquid stylet apparatus further comprises an indicator located within the tube, wherein a position of the indicator within the tube is visible.

17. A liquid stylet apparatus comprising:

a tube with a transparent portion and at least partially filled with a liquid;

a powering device in fluid communication with the tube;

a catheter located distally of the tube and attached in fluid communication with the tube, wherein the catheter is at least partially filled with the liquid;

a collection device located distally of the catheter and attached in fluid communication with the catheter, wherein the collection device is configured to engage a target area of a patient; and

an indicator contacting the liquid and located at least partially within the tube, wherein a position of the indicator within the tube is visible through the transparent portion,

wherein the indicator is fixed relative to liquid located immediately proximally and liquid located immediately distally of the indicator such that the indicator moves proximally when the surrounding liquid moves proximally due to tissue collection at the collection device.

18. The liquid stylet apparatus of claim 17 , the liquid stylet apparatus further comprising a valve that controls flow of the liquid between the tube and the catheter.