Tissue ablation devices and methods of using the same
Tissue ablation devices are provided. Aspects of the tissue ablation devices include an elongated member having a proximal and distal end. At the distal end are first and second jaws that are configured to apply ablation energy to tissue disposed between the jaws during use. Each jaw includes a surface proximal radiofrequency (RF) ablation energy component and a surface distal thermal ablation energy component. Also provided are systems that include a tissue ablation device operatively coupled to an energy source, as well as kits that include the devices and methods of using the devices in tissue ablation applications, including cardiac tissue ablation applications.
1. A tissue ablation device, the device comprising:
an elongated member having a proximal and distal end;
first and second jaws at the distal end that are configured to apply ablation energy to tissue disposed between the jaws during use;
the first jaw comprising a first surface proximal radiofrequency (RF) ablation energy component and a first surface distal thermal ablation energy component;
a first separator of a flexible material configured to separate the first surface proximal RF ablation energy component of the first jaw from the first surface distal thermal ablation energy component of the first jaw;
the second jaw comprising a second surface proximal RF ablation energy component and a second surface distal thermal ablation energy component;
a second separator of a flexible material configured to separate the second surface proximal RF ablation energy component of the second jaw from the second surface distal thermal ablation energy component of the second jaw; and
a connector at the proximal end for operatively connecting to an ablation energy source.
2. The tissue ablation device according to claim 1 , wherein each of the first surface proximal RF ablation energy component and the second surface proximal RF ablation energy component comprises one or more elongated electrodes.
3. The tissue ablation device according to claim 2 , wherein the first surface proximal RF ablation energy component comprises two elongated electrodes, and the second surface proximal RF ablation energy component comprises two other elongated electrodes.
4. The tissue ablation device according to claim 3 , wherein the elongated electrodes of each of the jaws are configured to have opposite polarity during use.
5. The tissue ablation device according to claim 1 , wherein each of the first surface distal thermal ablation energy component and the second surface distal thermal ablation energy component comprises a positive temperature co-efficient of resistivity (PTC) material.
6. The tissue ablation device according to claim 5 , wherein each of the first surface distal thermal ablation energy component and the second surface distal thermal ablation component comprises a linear arrangement of two or more PTC resistors.
7. The tissue ablation device according to claim 1 , wherein the first jaw comprises a first flex circuit comprising:
the first separator that is a flexible material having a tissue proximal side and a tissue distal side;
the first surface proximal RF ablation energy component present on the tissue proximal side of the first separator, wherein the first surface proximal RF ablation energy component comprises two elongated electrodes;
the first surface distal thermal ablation energy component present on the tissue distal side of the first separator, wherein the first surface distal thermal ablation energy component comprises two linear arrangements each made up of two or more PTC resistors; and
the second jaw comprises a second flex circuit comprising:
the second separator that is a flexible material having a tissue proximal side and a tissue distal side;
the second surface proximal RF ablation energy component present on the tissue proximal side of the second separator, wherein the second surface proximal RF ablation energy component comprises two elongated electrodes; and
the second surface distal thermal ablation energy component present on the tissue distal side of the second separator, wherein the second surface distal thermal ablation energy component comprises two linear arrangements each made up of two or more other PTC resistors.
8. The tissue ablation device according to claim 1 , wherein each of the first and second jaws is a multi-dimensional curved jaw.
9. The tissue ablation device according to claim 8 , wherein the multi-dimensional curved jaws are curved in two planes.
10. The tissue ablation device according to claim 1 , wherein at least one of the first and second jaws is collapsible into the elongated member.
11. The tissue ablation device according to claim 1 , wherein the first and second jaws are configured to not exceed a predetermined compressive force limit on tissue positioned between the jaws during use.
12. The tissue ablation device according to claim 11 , wherein the device comprises a constant force spring mechanism configured to limit the compressive force applied to tissue positioned between the jaws during use.
13. The tissue ablation device according to claim 1 , wherein the elongated member is rigid.
14. The tissue ablation device according to claim 13 , wherein the rigid elongated member comprises a bend.
15. The tissue ablation device according to claim 1 , wherein at least one of the first and second jaws comprises an illumination element.
16. The tissue ablation device according to claim 1 , wherein the device comprises a handle at the proximal end.
17. An ablation system comprising: the tissue ablation device according to claim 1 operatively connected to the ablation energy source.
18. A method of ablating tissue, the method comprising: positioning the tissue between the first and second jaws of the tissue ablation device according to claim 1 , wherein the tissue ablation device is operatively coupled to the ablation energy source; and applying ablation energy to the tissue disposed between the first and second jaws to ablate the tissue.