IP Library › Granted Patent US 10,612,036
Granted Patent B2
US 10,612,036 · App. 15/232,876 · Granted Apr 7, 2020

Engineered Cry6A insecticidal proteins

Inventors: Timothy D. Hey (Zionsville, IN); Xu Xiaoping (Yinchuan, CN); Todd P. Glancy (Fairmount, IN); Diaa Alabed (Carmel, IN); Sarah E. Worden (Indianapolis, IN); Nick X. Wang (Westfield, IN); Carla Ausmus (Pasadena, MD); Shao-Ching Hung (Midland, MI)
Assignee: DOW AGROSCIENCES LLC
C12N15/8286C07K14/325Y02A40/162
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Quick Facts
Patent No.
US 10,612,036
App. No.
15/232,876
Granted
Apr 7, 2020
Kind
B2
Abstract

Engineered and modified Cry6Aa insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.

Claims (12)

1. A modified Cry6Aa insecticidal protein comprising SEQ ID NO:35, SEQ ID NO:37, SEQ ID NO:39, SEQ ID NO:41, SEQ ID NO:43, SEQ ID NO:45, SEQ ID NO:47, SEQ ID NO:49, SEQ ID NO:64, SEQ ID NO:66, SEQ ID NO:68, SEQ ID NO:70, SEQ ID NO:72, SEQ ID NO:74, SEQ ID NO:76, SEQ ID NO:78, SEQ ID NO:80, SEQ ID NO:82, SEQ ID NO:84, SEQ ID NO:86, SEQ ID NO:88, SEQ ID NO:90, SEQ ID NO:92, SEQ ID NO:94, SEQ ID NO:96, SEQ ID NO:98, SEQ ID NO:100, SEQ ID NO:102, SEQ ID NO:104, SEQ ID NO:106, SEQ ID NO:108, SEQ ID NO:110, SEQ ID NO:112, SEQ ID NO:114, SEQ ID NO:116, SEQ ID NO:118, SEQ ID NO:120, SEQ ID NO:132, SEQ ID NO:136, SEQ ID NO:138, SEQ ID NO:140, or SEQ IDNO:144.

2. The modified Cry6Aa insecticidal protein of claim 1 , wherein the protein comprises SEQ ID NO:110, SEQ ID NO:112, SEQ ID NO:114, SEQ ID NO:116, SEQ ID NO:118, SEQ ID NO:120, SEQ ID NO:132, SEQ ID NO:140, or SEQ ID NO:144.

3. The modified Cry6Aa insecticidal protein of claim 1 , wherein the protein comprises SEQ ID NO:116, SEQ ID NO:118, SEQ ID NO:120, SEQ ID NO:140, or SEQ ID NO:144.

4. The modified Cry6Aa insecticidal protein of claim 1 , wherein the protein comprises SEQ ID NO:116.

5. A nucleic acid sequence encoding the modified Cry6Aa insecticidal protein of claim 1 .

6. A nucleic acid sequence encoding the modified Cry6Aa insecticidal protein of claim 2 .

7. A nucleic acid sequence encoding the modified Cry6Aa insecticidal protein of claim 3 .

8. A nucleic acid sequence encoding the modified Cry6Aa insecticidal protein of claim 4 .

9. A transgenic plant or plant part that comprises the nucleic acid sequence of claim 6 .

10. A method of controlling insect pest damage to plants which comprises preparing the transgenic plant of claim 9 and presenting said plant to an insect pest population.

11. The method of claim 10 wherein the insect pest damage is caused by insects of the order Coleoptera.

12. The method of claim 10 wherein the insect pest damage is caused by western corn rootworms.

Assignments (2)
CHANGE OF NAME Recorded Nov 8, 2021
From: DOW AGROSCIENCES LLC
To: CORTEVA AGRISCIENCE LLC
Reel/Frame 058044/0184 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 20, 2016
From: HEY, TIMOTHY D.; XU, XIAOPING; GLANCY, TODD P; WORDEN, SARAH E; WANG, NICK X; AUSMUS, CARLA; HUNG, SHAO-CHING; ALABED, DIAA
To: DOW AGROSCIENCES LLC
Reel/Frame 039803/0727 →
Continuity (2)
Provisional Application 62205797 · Aug 17, 2015
Related Publication 20170051304A1 · Feb 23, 2017