Therapeutic bacteriophage compositions
The present invention relates to a bacteriophage composition comprising one or more (suitably two or more, or three) bacteriophages selected from Sa87, J-Sa36, Sa83, J-Sa37, or mutants thereof, use of the same for medical or non-medical applications, kits, bandage, and wound dressing comprising the same.
1. A method of treating a Staphylococcus aureus bacterial infection, comprising administering a bacteriophage composition comprising one or more bacteriophages that infect and lyse Staphylococcus aureus selected from Sa87, J-Sa36, and Sa83.
2. A method of treating a pulmonary bacterial infection in a subject comprising administering a bacteriophage composition comprising one or more bacteriophages that infect and lyse Staphylococcus aureus selected from Sa87, J-Sa36, and Sa83 to the subject, wherein the bacterial infection comprises Staphylococcus aureus.
3. The method according to claim 1 , further comprising administering an antibiotic to the subject.
4. A method of killing Staphylococcus aureus bacteria on a surface, said method comprising applying a bacteriophage composition comprising one or more bacteriophages that infect and lyse Staphylococcus aureus selected from Sa87, J-Sa36, and Sa83 to the surface.
5. The method according to claim 4 , wherein the surface is the skin of a mammal, equipment, bedding, furniture, walls, floors, or combinations thereof.
6. A non-medical method of killing Staphylococcus aureus bacteria comprising applying to a food product or a crop a bacteriophage composition comprising one or more bacteriophages that infect and lyse Staphylococcus aureus selected from Sa87, J-Sa36, and Sa83.
7. The method according to claim 2 , further comprising administering an antibiotic to the subject.
8. The method according to claim 1 , wherein the bacteriophage composition comprises Sa87, J-Sa36, and Sa83.
9. The method according to claim 1 , wherein the bacteriophage composition consists essentially of Sa87, J-Sa36, and Sa83.
10. The method according to claim 2 , wherein the bacteriophage composition comprises Sa87, J-Sa36, and Sa83.
11. The method according to claim 2 , wherein the bacteriophage composition consists essentially of Sa87, J-Sa36, and Sa83.
12. The method according to claim 4 , wherein the bacteriophage composition comprises Sa87, J-Sa36, and Sa83.
13. The method according to claim 4 , wherein the bacteriophage composition consists essentially of Sa87, J-Sa36, and Sa83.
14. The method according to claim 4 , further comprising applying an antibiotic.
15. The method according to claim 6 , wherein the bacteriophage composition comprises Sa87, J-Sa36, and Sa83.
16. The method according to claim 6 , wherein the bacteriophage composition consists essentially of Sa87, J-Sa36, and Sa83.
17. The method according to claim 6 , further comprising use of an antibiotic.
18. The method according to claim 3 , wherein the antibiotic is a chemical antibiotic.
19. The method according to claim 7 , wherein the antibiotic is a chemical antibiotic.
20. The method according to claim 14 , wherein the antibiotic is a chemical antibiotic.
21. The method according to claim 17 , wherein the antibiotic is a chemical antibiotic.