IP Library Granted Patent US 10,676,757
Granted Patent B2
US 10,676,757 · App. 15/237,918 · Granted Jun 9, 2020

IRDIG17912 insecticidal Cry toxins

Inventors: Timothy D. Hey (Zionsville, IN); Janna Mai Armstrong (Indianapolis, IN); Ted Letherer (Indianapolis, IN); Audrey Jane Etter (Indianapolis, IN); Meghan L. Frey (Greenwood, IN); Haley Ellis (Indianapolis, IN); Kenneth E. Narva (Zionsville, IN); Xiaoping Xu (Yinchuan, CN); Krishna M. Madduri (Indianapolis, IN); Sek Yee Tan (Carmel, IN); Premchand Gandra (Zionsville, IN)
Assignee: DOW AGROSCIENCES LLC
C12N15/8286C07K14/325Y02A40/162
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Quick Facts
Patent No.
US 10,676,757
App. No.
15/237,918
Granted
Jun 9, 2020
Kind
B2
Abstract

Insecticidal toxins derived from Bacillus thuringiensis , polynucleotides encoding such toxins, use of such toxins to control plant pests, and transgenic plants that produce, and are protected, by these toxins are described.

Claims (11)

1. An engineered chimeric insecticidal toxin selected from the group consisting of SEQ ID NO: 8, SEQ ID NO: 10, SEQ ID NO: 12, SEQ ID NO: 14, SEQ ID NO: 16, and a toxin having at least 95% sequence identity with SEQ ID NO: 8, SEQ ID NO: 10, SEQ ID NO: 12, SEQ ID NO: 14, or SEQ ID NO: 16.

2. A DNA sequence encoding an engineered chimeric insecticidal toxin of claim 1 .

3. A nucleic acid construct comprising a nucleic acid sequence encoding an IRDIG17912 insecticidal toxin of SEQ ID NO: 2 or SEQ ID NO: 4, or a toxin having at least 95% sequence identity with SEQ ID NO: 2 or SEQ ID NO: 4, operably linked to a heterologous promoter capable of driving expression in a plant.

4. A nucleic acid construct comprising the DNA of claim 2 , operably linked to a heterologous-promoter capable of driving expression in a plant.

5. A transgenic plant or plant part comprising the toxin of claim 1 .

6. A transgenic plant or plant part comprising the nucleic acid construct of claim 3 .

7. A transgenic plant or plant part comprising the nucleic acid construct of claim 4 .

8. A method for controlling a western corn rootworm pest population comprising contacting members of said western corn rootworm pest population with the transgenic plant or plant part of claim 6 .

9. A method for controlling a western corn rootworm pest population comprising contacting members of said western corn rootworm pest population with the transgenic plant or plant part of claim 7 .

10. A method for controlling a western corn rootworm pest population comprising contacting members of said western corn rootworm pest population with a pesticidally effective amount of the insecticidal toxin of claim 1 .

11. A Pseudomonas fluorescens host strain engineered to express a DNA encoding an IRDIG17912 insecticidal toxin of SEQ ID NO: 2 or SEQ ID NO: 4, or a toxin having at least 95% sequence identity with SEQ ID NO: 2 or SEQ ID NO: 4.

Assignments (2)
CHANGE OF NAME Recorded Nov 8, 2021
From: DOW AGROSCIENCES LLC
To: CORTEVA AGRISCIENCE LLC
Reel/Frame 058044/0184 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 6, 2016
From: HEY, TIMOTHY D; ARMSTRONG, JANNA MAI; LETHERER, TED; ETTER, AUDREY JANE; FREY, MEGHAN L; MOWERY, HALEY R; NARVA, KENNETH; XIAOPING, XU; MADURI, KRISHNA M; TAN, SEK YEE; GANDRA, PREMCHAND
To: DOW AGROSCIENCES LLC
Reel/Frame 040534/0271 →
Continuity (2)
Provisional Application 62209586 · Aug 25, 2015
Related Publication 20170058293A1 · Mar 2, 2017