System and method for multi-axis imaging of specimens
A specimen holding and positioning apparatus operable to substantially non-movably maintain a specimen (e.g., an excised tissue specimen) in a fixed or stable orientation with respect to the apparatus during imaging operations (e.g., x-ray imaging), transport (e.g., from a surgery room to a pathologist's laboratory), and the like for use in facilitating accurate detection and diagnosis of cancers and/or other abnormalities of the specimen.
1. An apparatus for positionably retaining a tissue specimen for imaging, comprising:
a first positioning member comprising a portion thereof that is at least partially elastically deformable;
a second positioning member comprising a portion thereof that is at least partially elastically deformable, wherein the first and second positioning members are fixably positionable to allow the portions of the first and second positioning members to retain a tissue specimen therebetween within a specimen support volume of the apparatus, wherein first and second orthogonal axes of the apparatus extend through the specimen support volume, and wherein a reference plane extends between the portions of the first and second positioning members when the first and second positioning members are fixably positioned relative to each other;
a first volume extending about and along the first axis from a first external side of the apparatus to a second external side of the apparatus and encompassing the specimen support volume; and
a second volume extending about and along the second axis from a third external side of the apparatus to a fourth external side of the apparatus and encompassing the specimen support volume, wherein the first and second volumes are free of any portion having a density greater than either a density of the portion of the first positioning member or a density of the portion of the second positioning member.
2. The apparatus of claim 1 , wherein the first positioning member includes a body and an opening extending partially into the body, wherein the elastically deformable portion of the first positioning member is a bottom surface of the opening.
3. The apparatus of claim 2 , wherein the second positioning apparatus includes a body, wherein the elastically deformable portion of the second positioning member is a bottom surface of the body, and wherein the elastically deformable portion of the second positioning member is receivable in the opening of the first positioning member.
4. The apparatus of claim 1 , wherein the portions of the first and second positioning members comprise a polymeric material.
5. The apparatus of claim 4 , wherein the polymeric material is a foam.
6. The apparatus of claim 1 , wherein each of the first and second positioning members is a one-piece component.
7. The apparatus of claim 1 , further comprising a grid member comprising a series of grid lines across at least one surface thereof, wherein the grid member is removably positionable across the portion of one of the first and second positioning members.
8. The apparatus of claim 7 , wherein the grid member is removably positionable over the portion of the one of the first and second positioning members when the first and second positioning members are at partially separated from each other.
9. The apparatus of claim 1 , wherein the apparatus is free of non-deformable components within the first volume.
10. The apparatus of claim 1 , wherein the apparatus is free of non-deformable components within the second volume.