Systems and methods for blood sample preservation and hematocrit separation
A system for preserving a blood sample and removing hematocrit includes a casing, the casing having a sample port and a lateral flow strip in the casing, the lateral flow strip receiving a sample through the sample port, and flowing the sample down a length of the lateral flow strip.
1. A system for preserving a blood sample and removing hematocrit, comprising:
a casing, the casing having a sample port; and
a lateral flow strip in the casing, the lateral flow strip configured for receiving a sample through the sample port and flowing the sample down a length of the lateral flow strip:
a blood separation layer configured to remove hematocrit In the casing on top of the lateral flow strip, oriented in line with the sample port:
a sealable sample preservative enclosure: and
a desiccant received within the sample preservative enclosure,
the casing and contained lateral flow strip and blood separation layer having a first condition of being separate from the sample preservation enclosure for reception of a sample, the casing and contained lateral flow strip and blood separation layer having a second condition, after having received a sample, of being sealed within the sample preservative enclosure, the desiccant being effective to dry the sample within the sealed sample preservative enclosure, and
wherein the blood separation layer includes a screen side and an opposed felt side, and the lateral flow strip includes a screen side and an opposed felt side, the screen side of the blood separation and the uniform screen side of the lateral flow strip facing each other.
2. The system of claim 1 , wherein the blood separation layer is approximately a length of the sample port and the lateral flow strip is a length of the casing.
3. The system of claim 1 , wherein the casing includes a vent, the vent distal from the sample port.
4. The system of claim 3 , further comprising a nylon layer oriented in the casing adjacent the felt side of the lateral flow test strip.
5. The system of claim 4 , further comprising a cap, the cap sized to fit in the sample port of the casing.
6. The system of claim 5 , wherein the blood separation layer has been impregnated with inert ingredients to make it hydrophilic and allow red blood cell filtration.
7. The system of claim 6 , wherein the inert ingredients are poly vinyl alcohol and a wetting agent.
8. The system of claim 6 , wherein the inert ingredients are poly vinyl alcohol and lectins.
9. The system of claim 5 in which the cap is configured such that insertion of the cap into the sample port pushes the sample using air pressure through the blood separation layer and the lateral flow strip.
10. The system of claim 1 , in which the sample preservative enclosure comprises a pouch including the desiccant.
11. The system of claim 1 , in which the sample preservative enclosure comprises a vial including the desiccant.