Patent Application
App. No. 15/255,651
POLYMORPHIC FORMS ALPHA, BETA AND GAMMA OF RIFAXIMIN
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Abstract
Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
Claims (3)
1 . Rifaximin in polymorphic form α.
2 . Rifaximin in polymorphic form β.
3 . Rifaximin in polymorphic form γ.
Assignments (2)
MERGER
Recorded Nov 14, 2017
From: ALFA WASSERMANN S.P.A.
To: ALFASIGMA S.P.A.
Reel/Frame 045061/0645 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 5, 2016
From: VISCOMI, GIUSEPPE CLAUDIO; CAMPANA, MANUELA; BRAGA, DARIO; CONFORTINI, DONATELLA; CANNATA, VINCENZO; RIGHI, PAOLO; ROSINI, GOFFREDO; SEVERINI, DENIS
To: ALFA WASSERMANN S.P.A.
Reel/Frame 039946/0517 →