Devices and methods for heart valve repair
Devices and methods provide enhanced treatment of a cardiac valve annulus. Methods generally involve contacting an anchor delivery device with the valve annulus and releasing a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus. Anchors, which in some embodiments are super-elastic or shape memory self-securing anchors, are then drawn together to tighten the annulus. Devices generally include an elongate catheter having a housing at or near the distal end for releasably housing a plurality of coupled anchors. The housing may be flexible, may conform to a valve annulus, and in some embodiments may be coupled with an expandable member to enhance contact of the housing with annular tissue. In one embodiment, self-securing anchors lie approximately flat within the delivery device housing, allowing anchors with relatively large deployed shapes to be housed in and deployed from a relatively narrow delivery device.
1. A method of constricting tissue in a heart, the method comprising:
advancing an operational device to contact tissue of a tricuspid valve annulus of the heart, wherein the operational device comprises a lumen and a plurality of apertures in communication with the lumen for delivering a plurality of anchors therethrough;
delivering a plurality of tethered, self-securing anchors from the lumen of the operational device through the plurality of apertures to secure the anchors to the tissue of the tricuspid valve annulus; and
drawing the tethered, self-securing anchors together to constrict the tissue of the tricuspid valve annulus.
2. The method of claim 1 , wherein each of the self-securing anchors has a straight undeployed configuration and a curved deployed configuration.
3. The method of claim 2 , wherein each of the self-securing anchors comprises two sharpened tips and a loop therebetween, and when the anchor is in the deployed configuration, the two sharpened tips curve in opposite directions.
4. The method of claim 1 , wherein delivering the plurality of tethered, self-securing anchors comprises sequentially releasing each self-securing anchor from the operational device.
5. The method of claim 1 , wherein advancing an operational device to contact tissue of a tricuspid valve annulus comprises contacting tissue adjacent a tricuspid valve leaflet.
6. The method of claim 1 , wherein advancing, delivering and drawing are performed as part of an open heart surgical procedure.
7. The method of claim 1 , wherein advancing, delivering and drawing are performed without stopping the heart.
8. The method of claim 1 , wherein advancing, delivering and drawing are performed through one or more minimally invasive incisions.
9. The method of claim 1 , wherein drawing the anchors together comprises allowing a self-deforming coupling member coupled with the anchors to deform to constrict the tissue.
10. The method of claim 1 , wherein delivering the plurality of anchors from the operational device acts to secure at least one heart valve prosthesis to the tissue.
11. The method of claim 1 , wherein advancing, delivering and drawing are performed via intravascular access to the heart.
12. The method of claim 1 , further comprising deforming a flexible distal portion of the operational device to conform a distal portion of the operational device to a length of tricuspid annulus tissue prior to contacting the operational device with the length of tricuspid annulus tissue.
13. The method of claim 1 , wherein drawing the anchors together comprises cinching a tether coupled with the anchors.
14. The method of claim 13 , further comprising:
securing the tether to at least a terminal anchor of the plurality of anchors; and
cutting the tether to leave the cinched anchors secured to the tissue.
15. The method of claim 1 , further comprising visualizing the tissue of the tricuspid valve annulus.
16. The method of claim 15 , wherein visualizing is performed using a visualization device selected from the group consisting of an ultrasound device, an angioscopic device, a transesophageal echocardiogram device and a fluoroscopic device.