IP Library Granted Patent US 10,571,370
Granted Patent B2
US 10,571,370 · App. 15/271,097 · Granted Feb 25, 2020

Methods and machines for drying blood smears and an automatic smearing device

Inventors: Liang Zhang (Shenzhen, CN); Xuerong Li (Shenzhen, CN); Yuan Xiang (Shenzhen, CN)
Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
G01N1/2813F26B3/04F26B9/06
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Quick Facts
Patent No.
US 10,571,370
App. No.
15/271,097
Granted
Feb 25, 2020
Kind
B2
Abstract

A method and a machine for drying blood smears and an automatic smearing device are provided. In the method, a dry gas is used as a drying medium to dry a blood film on a blood smear in drying the blood smear, thus reducing drying time and the number of blood smears which are dried together. The dry gas is obtained by: first, removing a liquid from a pressurized gas, second, filtering a vapor, and finally, decompressing the dried pressurized gas to be a non-pressurized gas having lower humidity. In addition, the dry gas is further heated for further reducing the humidity of the dry gas. In order to prevent cell distortion from occurring, the heated dry gas is caused to gently flow over the blood smear in a direction which the blood film is spread.

Claims (27)

1. A method for drying a blood smear, said method comprising:

placing a blood drop on one end of a slide on a major surface of the slide;

spreading the blood drop substantially in a direction from the one end of the slide to another end of the slide, so that a blood smear having a blood film formed by the blood drop on the major surface of the slide is obtained;

acquiring a dry gas for drying the blood smear; and

flowing the dry gas over the major surface of the slide from the one end of the slide to the another end of the slide in substantially the same direction that the blood drop was spread.

2. The method according to claim 1 , further comprising:

providing a drying body in which the blood smear to be dried is inserted;

transferring the dry gas into the drying body; and

having the dry gas flow in the direction along which the blood film is spread inside the drying body.

3. The method according to claim 2 , further comprising:

heating the dry gas before having the dry gas flow in the direction along which the blood film is spread.

4. The method according to claim 3 , further comprising:

adjusting a flow rate to a predetermined value before heating the dry gas.

5. The method according to claim 2 , further comprising:

forming a gas flow from the dry gas between the blood film of the blood smear and a wall of the drying body.

6. The method according to claim 2 , wherein only one blood smear is inserted into the drying body in a single drying processing.

7. The method according to claim 1 , wherein acquiring a dry gas for drying the blood smear comprises:

compressing a gas into a pressurized gas;

drying the pressurized gas to obtain a dried pressurized gas; and

decompressing the dried pressurized gas to obtain a gas of atmospheric pressure as the dry gas.

8. The method according to claim 7 , wherein drying the pressurized gas comprises:

removing a liquid from the pressurized gas; or

removing a vapor from the pressurized gas.

9. The method of claim 1 , wherein the spreading of the blood drop is done with a spreader.

10. The method of claim 1 , wherein the slide has a long side extending between the one end and the another end.

11. The method of claim 1 , wherein the flowing the dry gas is without turbulent flow.

12. The method of claim 1 , wherein the dry gas is flowed in a pre-heated channel prior to flowing the dry gas over the major surface of the slide.

Assignments (2)
LICENSE Recorded Jun 24, 2022
From: SHENZHEN MINDRAY BIOMEDICAL ELECTRONICS CO., LTD.
To: SHENZHEN MINDRAY ANIMAL MEDICAL TECHNOLOGY CO., LTD.
Reel/Frame 060440/0796 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 21, 2016
From: ZHANG, LIANG; LI, XUERONG; XIANG, YUAN
To: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
Reel/Frame 039813/0291 →
Continuity (2)
Continuation PCTCN2014073774 · Mar 20, 2014
Related Publication 20170010192A1 · Jan 12, 2017