NEUROVASCULAR OCCLUSION DEVICE
A neurovascular occlusion device for occluding a vessel and a delivery system for delivering the occlusion device. The occlusion device can include a self-expandable support structure defining a concave occlusive component and an anchoring component separated by a neck component. The occlusive component can carry a functionally occlusive membrane configured to prevent substantially all fluid from flowing past the occlusion device when the occlusion device is expanded in the vessel.
1 . A neurovascular occlusion device for occluding blood flow in a vessel, comprising:
a support structure, self-expandable from a reduced cross-section for transluminal navigation to an enlarged cross-section for occluding a vessel, the support structure defining a concave occlusive component and an anchoring component separated by a neck component, the anchoring component comprising a ring of cells, the ring of cells comprising a first cell and a circumferentially adjacent second cell, a length of the first cell in a longitudinal direction being greater than a length of the second cell in the longitudinal direction.
2 . The neurovascular occlusion device of claim 1 , wherein the ring of cells comprises a third cell circumferentially adjacent the second cell, the length of the second cell in the longitudinal direction being shorter than a length of the third cell in the longitudinal direction.
3 . The neurovascular occlusion device of claim 1 , wherein the occlusive component comprises a ring of cells, each cell in the at least one ring having a same length.
4 . The neurovascular occlusion device of claim 1 , wherein nodes of each of the cells closest to the neck component are longitudinally aligned with each other.
5 . The neurovascular occlusion device of claim 1 , wherein the anchoring component is concave in a direction away from the concave occlusive component.
6 . The neurovascular occlusion device of claim 1 , wherein the support structure has an expansion ratio of at least about 8:1.
7 . The neurovascular occlusion device of claim 1 , wherein the expansion ratio is at least about 10:1.
8 . The neurovascular occlusion device of claim 1 , further comprising a functionally occlusive membrane without a guidewire lumen and carried by the occlusive component.
9 . The neurovascular occlusion device of claim 8 , wherein the functionally occlusive membrane is configured to prevent at least 90% of fluid flow from flowing past the occlusion device at 120 mmHg pressure.
10 . The neurovascular occlusion device of claim 1 , further comprising elongate markers positioned at a proximal end and/or a distal end of the occlusion device, a major axis of the elongate markers extending in a longitudinal direction of the occlusion device.
11 . The neurovascular occlusion device of claim 10 , wherein the elongate markers are rectangular.
12 . A neurovascular occlusion device for occluding blood flow in a vessel, comprising:
a support structure, self-expandable from a reduced cross-section for transluminal navigation to an enlarged cross-section for occluding a vessel, the support structure defining a concave occlusive component and an anchoring component separated by a neck component; the anchoring component comprising a ring of cells, each cell comprising a node that is closest to the neck component, the nodes being staggered such that each node is circumferentially and longitudinally offset from the node of a circumferentially adjacent cell and alternating nodes are longitudinally aligned with each other.
13 . The neurovascular occlusion device of claim 12 , wherein the concave occlusive component comprises a ring of cells, each cell comprising a node closest to the neck component, the nodes being longitudinally aligned with each other.
14 . The neurovascular occlusion device of claim 12 , further comprising a functionally occlusive membrane without a guidewire lumen and carried by the occlusive component.
15 . The neurovascular occlusion device of claim 14 , wherein the functionally occlusive membrane is configured to prevent more than 90% of fluid from flowing past the occlusion device at 120 mmHg pressure within three minutes.
16 . The neurovascular occlusion device of claim 14 , wherein the functionally occlusive membrane is porous and has no openings that are greater than a pore size of about 0.2 mm.
17 . The neurovascular occlusion device of claim 14 , wherein the functionally occlusive membrane has a same thickness along a length of the occlusive membrane.
18 . The neurovascular occlusion device of claim 17 , wherein the functionally occlusive membrane comprises a region of curvature and a cylindrical region, the cylindrical region having a greater number of layers than the region of curvature.
19 . The neurovascular occlusion device of claim 14 , wherein the functionally occlusive membrane comprises a region of curvature and a cylindrical region, a thickness of the region of curvature being greater than a thickness of the cylindrical region.
20 . The neurovascular occlusion device of claim 12 , wherein a thickness of the occlusive membrane is no greater than about 30 microns.
21 . The neurovascular occlusion device of claim 12 , wherein the anchoring component is concave in a direction away from the concave occlusive component.
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