Cosmetic compositions and uses thereof
Disclosed is a method for reducing the appearance of cellulite or improving the texture of skin in a target region of skin that has cellulite or rough skin texture, the method comprising topically applying a composition to the target region that includes an effective amount of a mixture of caffeine, escin, and an aqueous-alcoholic extract from Ascophyllum nodosum , wherein topical application of the composition reduces the appearance of cellulite or improves the texture of the skin.
1. A method for reducing the appearance of cellulite or improving the texture of skin in a target region of skin that has cellulite or rough skin texture, the method comprising topically applying a composition to the target region that includes an effective amount of a mixture of caffeine, escin, and an aqueous-alcoholic extract from Ascophyllum nodosum , wherein topical application of the composition reduces the appearance of cellulite or improves the texture of the skin.
2. The method of claim 1 , wherein the composition further comprises effective amounts of Rubus fruticosus extract, Argania spinosa kernel oil, Coleus barbatus extract, and glycolic acid.
3. The method of claim 2 , wherein the effective amounts are 0.001 to 10% by weight of the mixture of caffeine, escin, and the aqueous-alcoholic extract from Ascophyllum nodosum, 0.001 to 10% by weight of the aqueous-alcoholic extract from Rubus fruticosus leaf, 0.001 to 10% by weight of Argania spinosa kernel oil, 0.001 to 10% by weight of the Coleus barbatus root extract, and 0.001 to 10% by weight of glycolic acid.
4. The method of claim 2 , wherein the composition increases skin firmness or elasticity in said target region.
5. The method of claim 2 , wherein the composition increases lipolysis in adipocytes.
6. The method of claim 2 , wherein the composition decreases maturation of fat cells.
7. The method of claim 2 , wherein the target region comprises a dimple, and wherein the composition reduces the appearance of the dimple.
8. The method of claim 7 , wherein the composition reduces the difference between the peak and valley of the dimple.
9. The method of claim 2 , wherein the composition decreases the size of adipocytes in the target region.
10. The method of claim 9 , wherein the composition decreases the size of adipocytes in the target region having a diameter of equal to or greater than 40 μm or have a diameter between 40-160 μm.
11. The method of claim 10 , wherein between 5 and 20% of the adipocytes in the target region having a diameter of equal to or greater than 40 μm or have a diameter between 40-160 μm are decreased in size.
12. The method of claim 2 , wherein the composition increases the epidermal thickness of skin in the target region between 5 and 50%.
13. The method of claim 2 , wherein the composition increases triglyceride release from adipocytes in the target region.
14. The method of claim 1 , wherein the composition is formulated as a cream, lotion, or gel.
15. The method of claim 1 , wherein the composition is formulated as an emulsion.
16. The method of claim 1 , wherein the skin is leg skin, arm skin, torso skin, or skin in the pelvic region.
17. The method of claim 16 , wherein the composition is applied to the skin and remains on the skin for at least 5 minutes after topical application.
18. The method of claim 1 , wherein the mixture of caffeine, escin, and the aqueous-alcoholic extract is not encapsulated in nanoparticles.