IP Library Granted Patent US 10,532,211
Granted Patent B2
US 10,532,211 · App. 15/286,129 · Granted Jan 14, 2020

Method and system for neuromodulation and stimulation

Inventors: Roozbeh Ghaffari (Cambridge, MA); Shyamal Patel (Somerville, MA); Milan Raj (Cambridge, MA); Ryan McGinnis (Cambridge, MA)
Assignee: MC10, Inc.
A61N1/36139A61B5/0024A61B5/01A61B5/021A61B5/024A61B5/02405A61B5/0816A61B5/112A61B5/1118A61B5/4815A61B5/4836A61M5/1723A61M21/02A61N1/36067A61N1/36071A61N1/36114A61N1/36117A61N7/00A63B22/0023A63B22/025A63B22/04A63B24/0062A63B24/0075A63B24/0087G16H20/30G16H20/70G16H40/63G16H40/67G16H50/20A61B5/02438A61B5/04004A61B5/0488A61B5/0533A61B5/7275A61B2560/0242A61F7/00A61M5/14276A61M2021/0027A61M2021/0044A61M2021/0066A61M2205/3523A61M2205/3553A61M2205/3584A61M2205/8243A61M2230/06A61M2230/30A61M2230/42A61M2230/50A61M2230/60A61M2230/62A61M2230/65A61N5/0622A63B22/0076A63B22/02A63B22/0605A63B22/0664A63B2024/0065A63B2024/0078A63B2024/0093A63B2071/0081A63B2071/0625A63B2220/18A63B2220/30A63B2220/40A63B2220/805A63B2225/20A63B2225/50A63B2230/045A63B2230/06A63B2230/062A63B2230/10A63B2230/42A63B2230/425A63B2230/50A63B2230/60
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Quick Facts
Patent No.
US 10,532,211
App. No.
15/286,129
Granted
Jan 14, 2020
Kind
B2
Abstract

A system for controlling a therapeutic device and/or environmental parameters can include one or more body worn sensor devices that detect and report one or more physical, physiological, or biological parameters of a person in an environment. The sensor devices can communicate sensor data indicative of the one or more physical, physiological, or biological parameters of a person to an external hub that processes the data and communicates with the therapeutic device to provide a therapy (e.g., neuromodulation, neurostimulation, or drug delivery) as a function of the sensor data. In some embodiments, the therapeutic device can be implanted in the person. In some embodiments, the therapeutic device can be in contact with the skin of the person. The sensor devices can also communicate to the hub that communicates with one or more devices to change the environment as a function of the sensor data.

Claims (17)

1. A system comprising:

a sensing device having at least one sensor configured to sense at least one condition of a person in an environment, the sensing device including at least two rigid device islands, the at least two device islands coupled to each other via a flexible interconnect, one of the at least two rigid device islands including an electrode of the at least one sensor, the sensing device adaptable for contact to the skin of a person;

an external hub in communication with the sensing device and configured to receive sensor data from the sensing device; and

a therapeutic device configured to deliver therapy to the person upon receiving sensor data from the sensing device, the therapeutic device being physically separated from the sensing device and in wireless communication with the external hub or the sensing device.

2. The system according to claim 1 , wherein the therapeutic device includes an electrical or chemical actuator.

3. The system according to claim 1 , wherein the therapeutic device is configured to be placed in contact with a tissue of the person.

4. The system according to claim 3 , wherein the therapeutic device is in contact with an internal organ of the person.

5. The system according to claim 4 , wherein the therapeutic device is an implantable device.

6. The system according to claim 3 , wherein the therapeutic device is configured to be placed in contact with the skin of the person.

7. The system according to claim 1 , wherein the therapeutic device controls at least one of electrical stimulation, drug delivery, ultrasound stimulation, photostimulation, and thermal stimulation.

8. The system according to claim 1 , wherein the sensing device includes at least one of: an accelerometer, a temperature sensor, a gyroscope, a light sensor, an ExG sensor, a sound sensor, and one or more electrodes.

9. The system according to claim 1 , wherein the sensing device includes a processor, a memory, and/or a battery.

10. The system according to claim 1 , wherein the at least one condition of the person is selected from the group consisting of activity level, heart rate, heart rate variability, respiration rate, respiration rate variability, skin temperature, core temperature, blood pressure, gait, posture, muscle potential, range of motion, stride length, and sleep quality.

11. The system according to claim 1 , wherein the external hub is a smartphone.

12. The system according to claim 1 , further comprising a target device in communication with the external hub and configured to receive signals from the hub that result in a change in operation of the target device.

13. The system according to claim 12 , wherein the target device controls at least one of temperature, humidity, illumination or sound in the environment.

14. The system according to claim 1 , wherein the at least two device islands and the flexible interconnect are encapsulated in a stretchable material.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Nov 18, 2020
From: BRAEMAR ENERGY VENTURES III, L.P.; NORTH BRIDGE VENTURE PARTNERS VI, L.P.; NORTH BRIDGE VENTURE PARTNERS 7, L.P.; ABERDARE VENTURES IV, LP; ABERDARE PARTNERS IV, LP; WINDHAM LIFE SCIENCES PARTNERS, LP; WINDHAM-MC INVESTMENT I, LLC; LABORATORY CORPORATION OF AMERICA HOLDINGS
To: MC10, INC.
Reel/Frame 054456/0903 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2020
From: MC10, INC.
To: MEDIDATA SOLUTIONS, INC.
Reel/Frame 054476/0075 →
SECURITY INTEREST Recorded Apr 2, 2020
From: MC10, INC.
To: BRAEMAR ENERGY VENTURES III, L.P.; NORTH BRIDGE VENTURE PARTNERS VI, L.P.; NORTH BRIDGE VENTURE PARTNERS 7, L.P.; ABERDARE VENTURES IV, LP; ABERDARE PARTNERS IV, LP; WINDHAM LIFE SCIENCES PARTNERS, LP; WINDHAM-MC INVESTMENT I, LLC; LABORATORY CORPORATION OF AMERICA HOLDINGS
Reel/Frame 052296/0969 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 27, 2017
From: GHAFFARI, ROOZBEH; PATEL, SHYAMAL; RAJ, MILAN; MCGINNIS, RYAN
To: MC10, INC.
Reel/Frame 041102/0870 →
Continuity (2)
Provisional Application 62237214 · Oct 5, 2015
Related Publication 20170095670A1 · Apr 6, 2017
Cited By (5)
US 12,478,732 US 12,478,833 US 12,558,549 US 12,573,486 US 12,594,053