IP Library Granted Patent US 10,463,429
Granted Patent B2
US 10,463,429 · App. 15/288,949 · Granted Nov 5, 2019

Methods, devices, and systems for non-invasive delivery of microwave therapy

Inventors: Mark E. Deem (Mountain View, CA); Daniel E. Francis (Mountain View, CA); Jessi Ernest Johnson (Sunnyvale, CA); Steven W. Kim (Los Altos, CA); Alexey Salamini (San Francisco, CA)
Assignee: MIRADRY, INC.
A61B18/1815A61B18/18A61B34/10A61N5/02A61N5/025A61B90/37A61B2018/00005A61B2018/00017A61B2018/00023A61B2018/00029A61B2018/00041A61B2018/00452A61B2034/104A61N2005/007
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Quick Facts
Patent No.
US 10,463,429
App. No.
15/288,949
Granted
Nov 5, 2019
Kind
B2
Abstract

Methods, apparatuses and systems are provided for non-invasive delivery of microwave therapy. Microwave energy may be applied to epidermal, dermal and subdermal tissue of a patient to achieve various therapeutic and/or aesthetic results. In one embodiment, the microwave energy is applied to a target tissue via an energy delivery applicator connected to an energy generator. The energy delivery applicator may comprise one or more antennas, including monopole, dipole, slot and/or waveguide antennas (among others) that are used to direct the microwave energy to the target tissue. The energy delivery applicator may also comprise a cooling element for avoiding thermal destruction to non-target tissue and/or a suction device to localize thermal treatment at specific portions of a skin fold.

Claims (14)

1. A system for treating a skin tissue of a patient comprising:

a microwave energy generator, the microwave energy generator being configured to deliver microwave energy at a frequency of about 5.8 GHz;

an array of waveguide antennas configured for placement proximate to the skin tissue, the array of waveguide antennas being configured for simultaneous or sequential treatment of multiple sections of skin tissue and being configured to radiate electromagnetic radiation in the lowest-order Transverse Electric modes;

a cooling plate configured for placement in contact with the skin tissue;

a cooling fluid circuit at least partially superimposed on the cooling plate and configured to retain a liquid coolant between the cooling plate and the array of microwave antennas;

a suction element configured for elevating the skin tissue and placing the skin tissue in contact with the cooling plate;

wherein the array of microwave antennas are operatively coupled to the microwave energy generator, and wherein the array of microwave antennas are configured to deliver energy to the skin tissue sufficient to create a thermal effect in a target tissue within a skin tissue.

2. The system of claim 1 , wherein the cooling plate comprises a thermally-conductive cooling plate.

3. The system of claim 2 , wherein the thermally-conductive cooling plate is substantially transparent to microwave energy.

4. The system of claim 1 , wherein the cooling plate is configured to cool the skin tissue and physically separate the skin tissue from the array of microwave antennas.

5. The system of claim 1 , wherein the thermally-conductive cooling plate comprises a ceramic plate.

6. The system of claim 1 , wherein the liquid coolant is selected from the group consisting of water, deionized water, alcohol, and oil.

7. The system of claim 1 , wherein the suction element comprises a suction chamber configured for elevating target tissue comprising a portion of the skin tissue from underlying tissue.

8. The system of claim 1 , further comprising a temperature sensor comprising a thermocouple configured for monitoring the temperature of the skin tissue.

Assignments (20)
SECURITY INTEREST Recorded Oct 1, 2024
From: MIRADRY, INC.
To: WESTERN ALLIANCE BANK
Reel/Frame 068752/0533 →
RELEASE OF SECURITY INTEREST Recorded Nov 22, 2022
From: MIDCAP FINANCIAL TRUST
To: SIENTRA, INC.; MIST HOLDINGS, INC.; MIST, INC.; MIST INTERNATIONAL, INC.
Reel/Frame 061983/0573 →
RELEASE OF SECURITY INTEREST Recorded Nov 22, 2022
From: MIDCAP FUNDING IV TRUST
To: SIENTRA, INC.; MIST HOLDINGS, INC.; MIST, INC.; MIST INTERNATIONAL, INC.
Reel/Frame 061983/0486 →
RELEASE OF SECURITY INTEREST (TERM) Recorded Jun 22, 2021
From: MIDCAP FINANCIAL TRUST
To: MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
Reel/Frame 056648/0044 →
RELEASE OF SECURITY INTEREST (REVOLVING) Recorded Jun 22, 2021
From: MIDCAP FUNDING IV TRUST
To: MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
Reel/Frame 056648/0001 →
SECURITY INTEREST SUPPLEMENT (REVOLVING) Recorded Feb 23, 2021
From: SIENTRA, INC.; MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FUNDING IV TRUST, AS AGENT
Reel/Frame 055379/0016 →
REAFFIRMATION AGREEMENT AND AMENDMENT TO SECURITY AGREEMENT (TERM) Recorded Feb 23, 2021
From: SIENTRA, INC.; MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 055436/0001 →
SECURITY INTEREST Recorded Jul 2, 2019
From: SIENTRA, INC; MIRADRY HOLDINGS, INC.; MIRADRY, INC; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049650/0001 →
SECURITY INTEREST Recorded Jul 2, 2019
From: SIENTRA, INC; MIRADRY HOLDINGS, INC.; MIRADRY, INC; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049649/0450 →
SECURITY INTEREST Recorded Mar 13, 2019
From: MIDCAP FUNDING X TRUST (AS SUCCESSOR TO MIDCAP FINANCIAL TRUST)
To: MIDCAP FUNDING IV TRUST, SUCCESSOR AGENT
Reel/Frame 048588/0123 →
CHANGE OF NAME Recorded May 3, 2018
From: MIRAMAR TECHNOLOGIES, INC.
To: MIRADRY, INC.
Reel/Frame 045707/0330 →
CHANGE OF NAME Recorded May 3, 2018
From: MIRAMAR LABS, INC.
To: MIRAMAR TECHNOLOGIES, INC.
Reel/Frame 045706/0690 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 6, 2017
From: THE FOUNDRY, INC.
To: MIRAMAR LABS, INC.
Reel/Frame 044042/0761 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 6, 2017
From: THE FOUNDRY, INC.; MIRAMAR LABS, INC.; FRANCIS, DANIEL; JOHNSON, JESSI E.; KIM, STEVEN; SALAMINI, ALEXEY; SU, TED; CHUN, DONGHOON; BEN-HAIM, YOAV
To: MIRAMAR LABS, INC.
Reel/Frame 044042/0951 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 6, 2017
From: THE FOUNDRY, INC.; MIRAMAR LABS, INC.; DEEM, MARK E.; FRANCIS, DANIEL; JOHNSON, JESSI E.; KIM, STEVEN; SALAMINI, ALEXEY
To: MIRAMAR LABS, INC.
Reel/Frame 044043/0143 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 6, 2017
From: DEEM, MARK E.; GIFFORD, HANSON; KIM, STEVEN; SALAMINI, ALEXEY
To: THE FOUNDRY, INC.
Reel/Frame 044042/0664 →
RELEASE OF SECURITY INTEREST Recorded Aug 18, 2017
From: OXFORD FINANCE LLC
To: MIRAMAR TECHNOLOGIES, INC. F/K/A MIRAMAR LABS, INC.
Reel/Frame 043331/0505 →
SECURITY INTEREST Recorded Jul 28, 2017
From: SIENTRA, INC.; MIRAMAR LABS, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 043361/0130 →
SECURITY INTEREST Recorded Jul 28, 2017
From: SIENTRA, INC.; MIRAMAR LABS, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 043362/0811 →
SECURITY INTEREST Recorded Mar 8, 2017
From: MIRAMAR TECHNOLOGIES, INC.
To: OXFORD FINANCE LLC
Reel/Frame 041510/0935 →
Continuity (5)
Continuation 12450860
Provisional Application 60912899 · Apr 19, 2007
Provisional Application 61013274 · Dec 12, 2007
Provisional Application 61045937 · Apr 17, 2008
Related Publication 20170245929A1 · Aug 31, 2017
Cited By (11)
US 1,065,551 US 1,084,369 US 1,112,778 US 1,116,120 US 1,141,134 US 12,186,513 US 12,295,618 US 12,396,791 US 12,478,771 US 12,533,187 US 12,544,051