Bioabsorbable polymeric composition for a medical device
A biodegradable and biocompatible nontoxic polymeric composition is provided which includes a base material such as a crystallizable polymer, copolymer, or terpolymer, and a copolymer or terpolymer additive. Medical devices manufactured from the composition are also provided.
1. A bioabsorbable stem comprising a crystallized polymer composition, the polymer composition comprising: poly (L-lactide-co-Tri-methylene-carbonate) or poly (D-lactide-co-tri-methylene-carbonate) or poly (L-lactide-co-ε-caprolactone) or poly (D lactide-co-ε-caprolactone), in the form of block copolymers or blocky random copolymers.
2. The stem of claim 1 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone).
3. The stent of claim 1 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone).
4. The stent of claim 1 , further comprising poly (L-lactide) moiety, and/or a poly (D-lactide) moiety, and/or poly L-lactide-co-Peg moiety, and/or poly D-lactide-co-PEG moiety.
5. The stent of claim 4 , wherein the polymer comprises poly(L-lactide) and/or poly(D-lactide).
6. The stem of claim 3 , further comprising a poly (L-lactide) moiety, and/or a poly (D-lactide) moiety, and or poly L-lactide-co-PEG moiety, and/or poly D-lactide-co-PEG moiety.
7. The stem of claim 6 , wherein the polymer comprises poly(L-lactide).
8. The stem of claim 7 , wherein the polymer composition is further crystallized upon expansion of the stent.
9. The stem of claim 7 , wherein the stem is balloon-expandable.
10. The stent of claim 7 , wherein the stem comprises a hoop structure.
11. The stem of claim 7 , further comprising at least one radiopaque marker.
12. The stent of claim 7 , further including at least one pharmaceutical agent.
13. The stem of claim 7 , further including a barrier layer which contains at least one pharmaceutical agent.
14. The stent of claim 8 , wherein the polymer composition is crystallized in scaffold struts upon orthogonal strain deployment.
15. A bioabsorbable scaffold comprising a crystallized polymer composition, the polymer composition comprising: poly (L-lactide-co-Tri-methylene-carbonate) or poly (D-lactide-co-tri-methylene-carbonate) or poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone), in the form of block copolymers or blocky random copolymers.