Reduced-ethanol mouth rinse formulations
View Patent ↗Provided are oral care compositions comprising one or more polyol solvents having a total Hansen Solubility Parameter (HSP) of from about 23 to 28, one or more non-anionic bioactive agents, and an aqueous phase, wherein the oral care composition is essentially free of alkyl sulfate surfactants, as well as method of using such compositions in the oral cavity.
1. An oral care composition comprising one or more polyol solvents having a total Hansen Solubility Parameter (HSP) of from about 25 to 27.5, one or more non-anionic bioactive agents, and an aqueous phase, wherein the oral care composition is essentially free of alkyl sulfate surfactants.
2. The composition of claim 1 wherein said one or more polyol solvents are selected from the group consisting of 2-methyl-2,4-pentanediol, 1,2-butanediol, 2,2-dimethyl-1,3-propanediol, and mixtures of two or more thereof.
3. The composition of claim 1 wherein said one or more non-anionic bioactive agents are selected from the group consisting of thymol, eucalyptol, menthol, methyl salicylate, and combinations of two or more thereof.
4. The composition of claim 1 wherein said composition is free of alkyl sulfate surfactants.
5. The composition of claim 1 further comprising at least one alkyl ether sulfate.
6. The composition of claim 5 wherein said at least one alkyl ether sulfate comprises sodium laureth sulfate.
7. The composition of claim 1 further comprising at least one poloxamer surfactant.
8. The composition of claim 7 wherein said at least one poloxamer surfactant is selected from the group consisting of poloxamer 407, poloxamer 188, poloxamer 108, and combinations of two or more thereof.
9. The composition of claim 1 having an amount of C 2 -C 4 monohydric alcohol up to about 1.0% v/v4.
10. The composition of claim 1 further comprising sugar alcohol in an amount of from about 7% to about 30% w/v.
11. The composition of claim 10 wherein said sugar alcohol comprises sorbitol.
12. An oral care composition comprising one or more polyol solvents selected from the group consisting of 2-methyl-2,4-pentanediol, 1,2-butanediol, 2,2-dimethyl-1,3-propanediol, and mixtures of two or more thereof; one or more non-anionic bioactive agents selected from the group consisting of thymol, eucalyptol, menthol, methyl salicylate, and combinations of two or more thereof; sorbitol; and water, wherein the oral care composition is essentially free of alkyl sulfate surfactants.
13. The oral care composition of claim 12 further comprising a surfactant selected from the group consisting of sodium laureth sulfate, poloxamer 407, poloxamer 188, and combinations of two or more thereof.
14. The oral care composition of claim 13 wherein said surfactant comprises poloxamer 407.
15. The composition of claim 13 wherein said composition is free of alkyl sulfate surfactants.
16. The composition of claim 15 having an amount of C 2 -C 4 monohydric alcohol of about 1.0% v/v or less.
17. The composition of claim 13 comprising a total weight of from about 5% to about 30% by weight of said one or more polyol solvents, from about 0.001 to about 0.35% w/v of said one or more non-anionic bioactive agents; and from about 7% to about 30% w/v of said sorbitol.
18. A method of reducing the number of oral microorganisms responsible for one or more conditions selected from the group consisting of plaque, gingivitis, gum disease, oral malodor and combinations of two or more of such conditions in the oral cavity, said method comprising the step of applying a composition of claim 1 to a surface of the oral cavity.
19. A method of reducing the number of oral microorganisms responsible for one or more conditions selected from the group consisting of plaque, gingivitis, gum disease, oral malodor and combinations of two or more of such conditions in the oral cavity, said method comprising the step of applying a composition of claim 12 to a surface of the oral cavity.