Diagnosis of urothelial cancer
View Patent ↗The present invention provides a method and a solid state device for identifying the presence of urothelial cancer in a patient comprising assigning the subject to a sub-population according to smoking habits, measuring the level of each biomarker of a panel of biomarkers in one or more samples obtained from the subject; and correlating the measured levels of the panel of biomarkers with the likelihood of the subject having urothelial cancer such that the subject can be classified as having urothelial cancer or as being a control.
1. A method, comprising:
measuring the level of each biomarker of a panel of protein biomarkers in a urine sample obtained from a subject having a history of smoking, wherein the panel of biomarkers consists of:
urinary epidermal growth factor (EGF), urinary IL6, urinary vascular endothelial growth factor (VEGF) and urinary cytokeratin 18 (CK18).
2. A method according to claim 1 , wherein the subject is a patient presenting with haematuria.
3. The method according to claim 1 , wherein the urine and urinary biomarker levels are volume normalized.