IP Library Granted Patent US 10,907,185
Granted Patent B2
US 10,907,185 · App. 15/313,321 · Granted Feb 2, 2021

Enzymatic synthesis of soluble glucan fiber

Inventors: Qiong Cheng (Wilmington, DE); Robert Dicosimo (Chadds Ford, PA); Arthur Ouwehand (Inga, FI); Zheng You (Wilmington, DE); Jian Ping Lai (Wallingford, PA); Zheyong Yu (Shanghai, CN); Zhenghong Zhang (Shanghai, CN)
Assignee: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
C12P19/18A21D13/40A23C9/123A23G3/36A23G9/32A23L2/52A23L7/126A23L7/135A23L21/10A23L29/273A23L33/21A61K8/73A61K31/716A61K31/721A61Q19/00C08B37/0009C08L5/00C12P19/04C12P19/08C12Y204/01C12Y204/01005A23V2002/00A61K2800/10A61K2800/85C08L2205/16
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Quick Facts
Patent No.
US 10,907,185
App. No.
15/313,321
Granted
Feb 2, 2021
Kind
B2
Abstract

An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.

Claims (17)

1. A soluble α-glucan fiber composition, said soluble α-glucan fiber composition comprising:

(a) an α-(1,6) linkage consisting of at least 95% α-(1,6) glycosidic linkages;

(b) 1% or less α-(1,3) glycosidic linkages;

(c) less than 2% α-(1,3,6) glycosidic linkages; and

(d) less than 1.5% α-(1,4) glycosidic linkages; and said soluble α-glucan fiber has

(e) a weight average molecular weight of less than 20000 Daltons;

(f) a viscosity of less than 0.25 Pascal second (Pa·s) at 12 wt % in water at 20° C.;

(g) a dextrose equivalence (DE) in the range of 1 to 30;

(h) a digestibility of less than 12% as measured by the Association of Analytical Communities (AOAC) method 2009.01;

(i) a solubility of at least 20% (w/w) in pH 7 water at 25° C.; and

(j) a polydispersity index of less than 5.

2. A carbohydrate composition comprising: 0.01 to 99 wt % (dry solids basis) of the soluble α-glucan fiber composition of claim 1 .

3. The carbohydrate composition of claim 2 further comprising: a monosaccharide, a disaccharide, glucose, sucrose, fructose, leucrose, corn syrup, high fructose corn syrup, isomerized sugar, maltose, trehalose, panose, raffinose, cellobiose, isomaltose, honey, maple sugar, a fruit-derived sweetener, sorbitol, maltitol, isomaltitol, lactose, nigerose, kojibiose, xylitol, erythritol, dihydrochalcone, stevioside, α-glycosyl stevioside, acesulfame potassium, alitame, neotame, glycyrrhizin, thaumantin, sucralose, L-aspartyl-L-phenylalanine methyl ester, saccharine, maltodextrin, starch, potato starch, tapioca starch, dextran, soluble corn fiber, a resistant maltodextrin, a branched maltodextrin, inulin, polydextrose, a fructooligosaccharide, a galactooligosaccharide, an isomaltooligosaccharide, a xylooligosaccharide, an arabinoxylooligosaccharide, a nigerooligosaccharide, a gentiooligosaccharide, a filler, an excipient, or a binder.

4. A food product comprising the soluble α-glucan fiber composition of claim 1 or the carbohydrate composition of claim 2 or 3 .

5. A cosmetic composition, a pharmaceutical composition or a low carcinogenicity composition comprising the soluble α-glucan fiber composition of claim 1 .

6. A food composition suitable for consumption by animals comprising the soluble α-glucan fiber composition of claim 1 .

7. A composition comprising 0.01 to 99 wt % (dry solids basis) of the soluble α-glucan fiber composition of claim 1 and an additional agent selected from a synbiotic, a peptide, a peptide hydrolysate, a protein, a protein hydrolysate, a soy protein, a dairy protein, an amino acid, a polyol, a polyphenol, a vitamin, a mineral, an herbal, an herbal extract, a fatty acid, a polyunsaturated fatty acid (PUFAs), a phytosteroid, betaine, a carotenoid, a digestive enzyme, or a probiotic organism.

Assignments (10)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 28, 2020
From: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
To: NUTRITION & BIOSCIENCES USA 4, INC.
Reel/Frame 055028/0496 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 16, 2019
From: DUPONT US HOLDING, LLC
To: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
Reel/Frame 050381/0449 →
CORRECTIVE ASSIGNMENT TO CORRECT THE DESIGNATION OF ASSIGNEE AS A DELAWARE CORPORATION TO A DELAWARE LIMITED LIABILITY COMPANY PREVIOUSLY RECORDED ON REEL 049880 FRAME 0001. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Aug 28, 2019
From: E. I. DU PONT DE NEMOURS AND COMPANY
To: DUPONT US HOLDING, LLC
Reel/Frame 051502/0610 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 26, 2019
From: E. I. DU PONT DE NEMOURS AND COMPANY
To: DUPONT US HOLDING, LLC
Reel/Frame 049880/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2017
From: OUWEHAND, ARTHUR
To: DANISCO SWEETENERS OY
Reel/Frame 043534/0078 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2017
From: DANISCO SWEETENERS OY
To: DUPONT NUTRITION BIOSCIENCES APS
Reel/Frame 043534/0188 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2017
From: YU, ZHEYONG; ZHANG, ZHENGHONG
To: DANISCO CHINA HOLDING CO., LTD
Reel/Frame 043534/0363 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2017
From: DANISCO CHINA HOLDING CO LTD.
To: DUPONT NUTRITION BIOSCIENCES APS
Reel/Frame 043534/0462 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2017
From: DUPONT NUTRITION BIOSCIENCES APS
To: E I DU PONT DE NEMOURS AND COMPANY
Reel/Frame 043534/0545 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2017
From: CHENG, QIONG; LAI, JIAN PING; DICOSIMO, ROBERT; YOU, ZHENG
To: E I DU PONT DE NEMOURS AND COMPANY
Reel/Frame 043533/0975 →