IP Library Granted Patent US 10,751,123
Granted Patent B2
US 10,751,123 · App. 15/336,887 · Granted Aug 25, 2020

Thermoablation probe

Inventors: Eric Leuthardt (St. Louis, MO); Jenna Gorlewicz (Edwardsville, IL); Mahmood Rezapour (Glen Carbon, IL)
Assignees: Washington University; Board of Trustees of Southern Illinois University
A61B18/22A61B2018/00023A61B2018/00446A61B2018/00577A61B2018/00714A61B2018/00821A61B2018/2005A61B2018/2238A61B2018/2288A61B2090/3762
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Quick Facts
Patent No.
US 10,751,123
App. No.
15/336,887
Granted
Aug 25, 2020
Kind
B2
Abstract

A thermoablation probe for performing an interstitial thermal therapy (ITT) procedure on a brain lesion generally includes a rigid sheath and a flexible treatment device telescopically slidable within the sheath. The treatment device has a substantially continuous covering and a shape-memory wire enveloped by the covering.

Claims (14)

1. A thermoablation probe system for performing an interstitial thermal therapy (ITT) procedure on a brain lesion, said system comprising:

a laser light source for generating and selectively transmitting ablative electromagnetic energy;

a probe mount configured for attaching to a skull;

an MRI compatible thermoablation probe configured for insertion through the probe mount and into the skull, the thermoablation probe comprising:

a rigid sheath; and

a flexible laser ablation device telescopically slidable within the sheath, wherein the flexible laser ablation device is coupled to the laser light source, wherein the laser ablation device is pre-curved to follow a predefined curvature trajectory upon deployment from the sheath, wherein the laser ablation device is configured for emitting the ablative electromagnetic energy along the predefined curvature trajectory upon the deployment, wherein the laser ablation device has a covering with an outer surface that is entirely free of edges and a shape-memory wire, a laser fiber, a thermocouple, a cooling tube and a distalmost gas-filled chamber, each hermetically sealed within the covering, and

a control unit operatively coupled to the thermoablation probe and the probe mount; and

wherein the probe mount is operable remotely by the control unit to maneuver the thermoablation probe relative to the skull.

2. The thermoablation probe system set forth in claim 1 wherein the laser ablation device is rotatable within the sheath to follow a predefined three-dimensional curved surface, along which the predefined curvature trajectory extends, upon deployment from the sheath.

3. The thermoablation probe system set forth in claim 1 wherein the shape-memory wire is made of nickel-titanium.

4. The thermoablation probe system set forth in claim 1 wherein the laser ablation device has insulating material that surrounds the wire within the covering.

5. The thermoablation probe system set forth in claim 1 wherein the laser ablation device is deployable from the sheath along a three-dimensional curved surface comprising the plurality of predefined target points.

6. The thermoablation probe system set forth in claim 1 , wherein the covering is tubular.

7. The thermoablation probe system set forth in claim 1 wherein the shape-memory wire is made of a shape-memory alloy.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 28, 2016
From: LEUTHARDT, ERIC
To: WASHINGTON UNIVERSITY
Reel/Frame 040157/0064 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 28, 2016
From: GORLEWICZ, JENNA; REZAPOUR, MAHMOOD
To: BOARD OF TRUSTEES SOUTHERN ILLINOIS UNIVERSITY
Reel/Frame 040157/0160 →
Continuity (2)
Provisional Application 62248917 · Oct 30, 2015
Related Publication 20170119467A1 · May 4, 2017
Cited By (1)
US 12,558,159