3-methanesulfonylpropionitrile for treating inflammation and pain
The present invention relates to purified 3-methanesulfonylpropionitrile or a pharmaceutically acceptable salt thereof, and a method for preparing such compound. The compound has at least 90% (w/w) purity. The present invention is also directed to a pharmaceutical composition comprises the purified compound and a pharmaceutically acceptable carrier. The present invention is further directed to a method for treating inflammation, inflammatory-related disorders, or pain, by administering 3-methanesulfonylpropionitrile or a pharmaceutically acceptable salt or solvate thereof to a subject in need thereof.
1. A method of reducing or alleviating symptoms of localized manifestations of inflammation characterized by acute or chronic swelling, pain, or redness, comprising the steps of:
identifying a subject suffering from localized manifestations of inflammation, and
administering to the subject a compound of 3-methanesulfonylpropionitrile, or a pharmaceutically acceptable salt thereof, in an amount effective to treat the localized manifestations of inflammation.
2. The method according to claim 1 , wherein said symptoms are characterized by localized acute or chronic swelling.
3. The method according to claim 1 , wherein said compound is topically administered.
4. A method of treating inflammation and/or pain associated with inflammatory joints, ligaments, tendons, bone, muscles, or fascia, comprising the steps of:
identifying a subject in need thereof, and
administering to the subject 3-methanesulfonylpropionitrile, or a pharmaceutically acceptable salt thereof, in an amount effective to treat the inflammation and/or pain associated with joints, ligaments, tendons, bone, muscles, or fascia.
5. The method according to claim 4 , wherein said method treats inflammation and/or pain associated with rheumatoid arthritis.
6. The method according to claim 4 , wherein said method treats inflammation and/or pain associated with osteoarthritis.
7. The method according to claim 4 , wherein said method treats inflammation and/or pain associated with gout.
8. The method according to claim 4 , wherein said method treats inflammation and/or pain associated with tendonitis.
9. The method according to claim 4 , wherein said compound is orally administered.
10. The method according to claim 4 , wherein said compound is topically administered.