IP Library Granted Patent US 9,848,973
Granted Patent B2
US 9,848,973 · App. 15/362,223 · Granted Dec 26, 2017

Porous devices and processes for producing same

Inventors: Wei-Hsiang Chang (Duluth, GA); Stephen Lee Laffoon (Atlanta, GA); Christopher S. D. Lee (Atlanta, GA); David Lee Safranski (Atlanta, GA)
Assignee: VERTERA, INC
A61F2/0077A61B6/12A61B6/50A61B90/39A61F2/44A61L27/18A61L27/50A61L27/56A61L31/06B29C44/0461B29C44/3415B29C67/202C08J9/0085C08J9/26A61B2090/3966A61F2002/0081A61F2002/0086A61F2210/0071A61F2250/0098A61L2430/38B29K2071/00B29L2031/753B29L2031/7546C08J2201/0446C08J2371/00
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Quick Facts
Patent No.
US 9,848,973
App. No.
15/362,223
Granted
Dec 26, 2017
Kind
B2
Abstract

A method for making a polymer with a porous layer from a solid piece of polymer is disclosed. In various embodiments, the method includes heating a surface of a solid piece of polymer to a processing temperature and holding the processing temperature while displacing a porogen layer through the surface of the polymer to create a matrix layer of the solid polymer body comprising the polymer and the porogen layer. In at least one embodiment, the method also includes removing at least a portion of the layer of porogen from the matrix layer to create a porous layer of the solid piece of polymer.

Claims (46)

1. A medical device for promoting tissue ingrowth, the medical device comprising a thermoplastic body defining a porous surface formed from a plurality of pores, each of the pores extending a defined distance from a first face into the thermoplastic body, wherein:

the thermoplastic body comprises a first particular percentage of hydroxyl groups;

the porous surface comprises a second particular percentage of hydroxyl groups, wherein the second particular percentage of hydroxyl groups is greater than the first particular percentage of hydroxyl groups;

an interconnectivity between the plurality of pores is at least 99%; and

an interfacial shear strength between the porous surface and the thermoplastic body is at least about 17 MPa.

2. The medical device of claim 1 , further comprising at least one marker for detecting the medical device on an x-ray.

3. The medical device of claim 2 , wherein the at least one marker comprises a radiolucent material.

4. The medical device of claim 3 , wherein the at least one marker further comprises a radiopaque material.

5. The medical device of claim 2 , wherein the at least one marker comprises a radiopaque metal.

6. The medical device of claim 5 , wherein the radiopaque metal is tantalum.

7. The medical device of claim 2 , wherein the at least one marker is substantially cylindrical, rectangular, triangular, or conical.

8. The medical device of claim 7 , wherein the at least one marker is substantially cylindrical.

9. The medical device of claim 8 , wherein the substantially cylindrical marker can be inserted into a portion of the thermoplastic body.

10. The medical device of claim 8 , wherein substantially cylindrical marker can be inserted into a portion of the thermoplastic body and extends vertically through the thermoplastic body.

11. The medical device of claim 1 , wherein the thermoplastic body further defines a second porous surface formed from a plurality of pores, each of the pores extending about the defined distance from a second face into the thermoplastic body.

12. The medical device of claim 11 , wherein:

the medical device further comprises at least one marker for detecting the medical device on an x-ray; and

the at least one marker extends from the top face of the porous surface through the thermoplastic body to the bottom face of the second porous surface.

13. The medical device of claim 12 , wherein the at least one marker is positioned so that it extends vertically through the medical device and the end-surfaces of the marker are substantially flush with porous faces of the thermoplastic body.

14. The medical device of claim 11 , wherein the defined distance is approximately 0.5 mm to 1.0 mm.

15. The medical device of claim 14 , wherein the defined distance is approximately 0.7 mm.

16. The medical device of claim 1 , wherein the thermoplastic body comprises polyetheretherketone (PEEK).

17. The medical device of claim 1 , wherein:

the thermoplastic body comprises a first particular carbon to oxygen atomic ratio; and

the porous surface comprises a second particular carbon to oxygen atomic ratio, wherein the second particular carbon to oxygen atomic ratio is substantially the same as the first particular carbon to oxygen atomic ratio.

18. The medical device of claim 1 , wherein the expulsion resistance of the medical device is at least about 1.5 times greater than the expulsion resistance of a medical device of a similar material, with no porous layers.

19. The medical device of claim 1 , wherein the porous surface has a particular wettability, and wherein the particular wettability is greater than a wettability of the thermoplastic body.

20. The medical device of claim 1 , wherein the thermoplastic body is substantially solid.

21. The medical device of claim 1 , wherein the thermoplastic body comprises multiple voids and is substantially hollow.

22. A medical device for promoting tissue ingrowth, the medical device comprising a body defining a porous surface formed from a plurality of pores, each of the pores extending a defined distance from a top face into the body, and at least one marker for detecting the medical device on an x-ray, wherein:

the body comprises a first particular percentage of hydroxyl groups;

the porous surface comprises a second particular percentage of hydroxyl groups, wherein the second particular percentage of hydroxyl groups is greater than the first particular percentage of hydroxyl groups;

an interconnectivity between the plurality of pores is at least 99%; and

an interfacial shear strength between the porous surface and the body is at least about 17 MPa.

23. The medical device of claim 22 , wherein the body comprises polyetheretherketone (PEEK).

24. The medical device of claim 22 , wherein:

the body comprises a first particular carbon to oxygen atomic ratio; and

the porous surface comprises a second particular carbon to oxygen atomic ratio, wherein the second particular carbon to oxygen atomic ratio is substantially the same as the first particular carbon to oxygen atomic ratio.

25. The medical device of claim 22 , wherein the expulsion resistance of the medical device is at least about 1.5 times greater than the expulsion resistance of a medical device of a similar material, with no porous layers.

26. The medical device of claim 22 , wherein the porous surface has a particular wettability, and wherein the particular wettability is greater than a wettability of the body.

27. The medical device of claim 22 , wherein the body is substantially solid.

28. A medical device for promoting tissue ingrowth, the medical device comprising a thermoplastic body defining a porous surface formed from a plurality of pores, each of the pores extending from a top face into the thermoplastic body, and at least one tantalum marker for detecting the medical device on an x-ray, wherein:

the thermoplastic body comprises a first particular percentage of hydroxyl groups;

the porous surface comprises a second particular percentage of hydroxyl groups, wherein the second particular percentage of hydroxyl groups is greater than the first particular percentage of hydroxyl groups;

an interconnectivity between the plurality of pores is at least 99%; and

the porous surface has a particular wettability, and wherein the particular wettability is greater than a wettability of the thermoplastic body.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2022
From: VERTERA, INC.
To: NUVASIVE, INC.
Reel/Frame 061669/0954 →
SECURITY INTEREST Recorded Feb 28, 2020
From: NUVASIVE, INC.; NUVASIVE CLINICAL SERVICES MONITORING, INC.; NUVASIVE CLINICAL SERVICES, INC.; NUVASIVE SPECIALIZED ORTHOPEDICS, INC.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 052918/0595 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 28, 2017
From: CHANG, WEI-HSIANG; LAFFOON, STEPHEN; LEE, CHRISTOPHER; SAFRANSKI, DAVID
To: VERTERA, INC.
Reel/Frame 043126/0074 →
Continuity (4)
Continuation 14752762 · Jun 26, 2015
Continuation In Part 14587856 · Dec 31, 2014
Provisional Application 62017834 · Jun 26, 2014
Related Publication 20170071718A1 · Mar 16, 2017