Methods for treating inflammation and pain
The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an ω-(methanesulfonyl)alkenylnitrile compound, or a pharmaceutically acceptable salt thereof. The present invention is also directed to a method for treating inflammation, inflammatory-related disorders, or pain, by administering an ω-(methanesulfonyl)alkenylnitrile compound or a pharmaceutically acceptable salt or solvate thereof to a subject in need thereof. The present invention is further directed to a method for potentiating the analgesic effects of morphine, by administering an effective amount of 3-(methylsulfonyl)acrylonitrile to a subject who is being treated with morphine and is suffering from pain. Oral and topical administration are preferred.
1. A method for treating pain, comprising:
administering to the subject suffering from pain an effective amount of morphine and an effective amount of 3-(methylsulfonyl)acrylonitrile.
2. The method according to claim 1 , wherein said pain is nociceptive pain.
3. A method for potentiating the analgesic effects of morphine, comprising:
administering an effective amount of 3-(methylsulfonyl)acrylonitrile to a subject who is being treated with morphine and is suffering from pain.
4. The method according to claim 3 , wherein said pain is nociceptive pain.
5. The method according to claim 3 , wherein said administering is by oral administration.