Reduced extravasation of bone cement
View Patent ↗The risk of bone cement extravaation can be reduced by delivering a calcium-dependent polymerizing sealant into a bone structure prior to delivery of bone cement into that structure. The polymerization of the sealant in response to the calcium within the bone structure can fill cracks and any other potential cement leakage paths, thereby minimizing the potential for subsequent extravaation. The benefits of the use of a calcium-dependent polymerizing sealant can be provided in any procedure involving the use of bone cement, such as spinal fixation, vertebroplasty, and kyphoplasty, among others.
1. A method comprising:
delivering a calcium-dependent polymerizing sealant into a bone structure;
allowing the calcium-dependent polymerizing sealant to polymerize in the bone structure; and
subsequently delivering bone cement into the bone structure.
2. The method of claim 1 , wherein the calcium-dependent polymerizing sealant comprises sodium alginate.
3. The method of claim 1 , further comprising placing a bone screw into the bone structure.
4. The method of claim 3 , wherein delivering the calcium-dependent polymerizing sealant comprises urging the calcium-dependent polymerizing sealant through fenestrations in the bone screw, and wherein subsequently delivering the bone cement comprises urging the bone cement through the fenestrations in the bone screw.
5. The method of claim 3 , wherein the bone structure comprises a vertebral body, and wherein placing the bone screw into the bone structure comprises inserting the bone screw into a pedicle of the vertebral body.
6. The method of claim 1 , wherein the bone structure comprises a vertebral body, and wherein delivering the calcium-dependent polymerizing sealant comprises: inserting a needle into the vertebral body; and injecting the calcium-dependent polymerizing sealant into cancellous bone within the vertebral body through the needle.
7. The method of claim 6 , wherein subsequently delivering the bone cement comprises injecting the bone cement into the cancellous bone through the needle.
8. The method of claim 6 , wherein subsequently delivering the bone cement comprises: inserting a second needle into the vertebral body; and injecting the bone cement into the cancellous bone through the second needle.
9. The method of claim 1 , further comprising creating a cavity in the bone structure, and wherein subsequently delivering the bone cement comprises delivering the bone cement into the cavity.
10. The method of claim 9 , wherein the bone structure comprises cancellous bone, and wherein creating the cavity in the bone structure comprises creating the cavity in the cancellous bone.
11. The method of claim 9 , wherein the bone structure comprises a vertebral body, and wherein creating the cavity in the bone structure comprises: establishing an access path to the vertebral body; inserting a cavity creation device into cancellous bone within the vertebral body; and creating the cavity in the cancellous bone using the cavity creation device.
12. The method of claim 11 , wherein the cavity creation device comprises an inflatable bone tamp, and wherein creating the cavity comprises inflating the inflatable bone tamp in the cancellous bone.
13. The method of claim 11 , wherein establishing the access path comprises docking a cannula with the vertebral body, and wherein inserting the cavity creation device comprises placing the cavity creation device into the cannula.
14. The method of claim 13 , wherein delivering the calcium-dependent polymerizing sealant comprises: placing a first nozzle into the cannula; and delivering the calcium-dependent polymerizing sealant through the first nozzle into the cavity.
15. The method of claim 14 , wherein subsequently delivering the bone cement comprises delivering the bone cement through the first nozzle into the cavity.
16. The method of claim 14 , wherein subsequently delivering the bone cement comprises: placing a second nozzle into the cannula; and delivering the bone cement through the second nozzle into the cavity.
17. The method of claim 1 , wherein the calcium-dependent polymerizing sealant is delivered into the bone structure before the bone cement is delivered into the bone structure.
18. A method comprising:
delivering a calcium-dependent polymerizing sealant into a bone structure using a high pressure injection system, the calcium-dependent polymerizing sealant comprising an alginate;
allowing the calcium-dependent polymerizing sealant to polymerize in the bone structure; and
subsequently delivering bone cement into the bone structure using a second injection system.
19. A method comprising:
delivering a calcium-dependent polymerizing sealant into a vertebral; body using a syringe, the calcium-dependent polymerizing sealant comprising sodium alginate;
allowing the calcium-dependent polymerizing sealant to polymerize in the bone structure; and
subsequently delivering bone cement into the bone structure using the syringe,
wherein the calcium-dependent polymerizing sealant is disposed in the first chamber prior to being injected into the bone structure and the bone cement is disposed in the second chamber prior to being injected into the bone structure.