Topical cosmetic compositions
Disclosed are compositions and methods for their use for reducing tumor necrosis factor alpha (TNF-α) and/or vascular endothelial growth factor (VEGF) production in skin cells by topically applying to skin in need thereof, a composition comprising an effective amount of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or both, or extracts thereof, to reduce TNF-α or VEGF production in skin cells.
1. A method of treating inflamed skin by reducing tumor necrosis factor alpha (TNF-α) or vascular endothelial growth factor (VEGF) production in skin cells, the method comprising topically applying to inflamed skin, a composition comprising 0.01 wt. % to 0.5 wt. % of an aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof to reduce TNF-α or VEGF production in skin cells to treat the inflamed skin, wherein the composition further comprises at least 50 wt. % water.
2. The method of claim 1 , wherein the composition comprises an aqueous extract of Opuntia ficus - indica tuna.
3. The method of claim 2 , wherein the composition is applied to erythemic skin.
4. The method of claim 2 , wherein the composition is applied to a fine line or wrinkle.
5. The method of claim 2 , wherein the composition is applied to the periorbital area of a person's face.
6. The method of claim 1 , wherein the composition is applied to rosacea or psoriasis.
7. The method of claim 1 , wherein the composition does not include a hydrocarbon, a silicone fluid, an organic sunscreen, chia seed oil, an extract of common mallow, a hydrogenated polymer, and a glyceryl glucoside.
8. The method of claim 1 , wherein the composition comprises 0.01 wt. % to 0.1 wt. % of the Opuntia ficus - indica tuna, Opuntia ficus - indica nopales, or both, or extracts thereof.
9. The method of claim 1 , wherein the composition comprises an effective amount of an aqueous extract of Opuntia ficus - indica nopal.
10. The method of claim 1 , wherein the composition is formulated as a serum comprising 60 to 70 wt. % water, and further comprises:
butylene glycol;
cyclopentasiloxane;
hydrogenated polydecene;
dimethicone/vinyl dimethicone cross polymer;
capryl glycol;
1,2-hexanediol;
hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer;
polysorbate 20;
squalane; and
-panthenol.
11. The method of claim 1 , wherein the composition is formulated as a serum and further comprises:
water;
glycerin;
acrylates/C 10-30 alkyl acrylate crosspolymer;
disodium ethylenediaminetetraacetic acid;
triethanolamine;
polydimethylsiloxane;
polymethyl methylacrylate;
glyceryl stearate;
pentylene glycol;
ethylhexyl isononanoate;
cetyl alcohol;
butyrosperum parkii butter;
zea mays germ oil;
cetyl phosphate;
cetearyl alcohol; and
ceteareth-33.