IP Library Granted Patent US 10,231,779
Granted Patent B2
US 10,231,779 · App. 15/382,436 · Granted Mar 19, 2019

Ablation catheter with high-resolution electrode assembly

Inventors: Dorin Panescu (San Jose, CA); Eric Andrew Schultheis (Sunnyvale, CA); Josef Vincent Koblish (Sunnyvale, CA); Jessi E. Johnson (Sunnyvale, CA)
Assignee: Epix Therapeutics, Inc.
A61B18/1492A61B5/01A61B5/0422A61B5/068A61B5/150954A61B5/6852A61B18/1206A61B2018/0016A61B2018/00023A61B2018/00029A61B2018/00083A61B2018/00101A61B2018/00351A61B2018/00357A61B2018/00577A61B2018/00642A61B2018/00672A61B2018/00678A61B2018/00702A61B2018/00714A61B2018/00761A61B2018/00797A61B2018/00815A61B2018/00821A61B2018/00839A61B2018/00875A61B2018/128A61B2018/1467A61B2217/007A61B2218/002A61B2562/046
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Quick Facts
Patent No.
US 10,231,779
App. No.
15/382,436
Granted
Mar 19, 2019
Kind
B2
Abstract

According to some embodiments, a medical instrument (for example, an ablation device) comprises an elongate body having a proximal end and a distal end, an energy delivery member positioned at the distal end of the elongate body, a first plurality of temperature-measurement devices carried by or positioned within the energy delivery member, the first plurality of temperature-measurement devices being thermally insulated from the energy delivery member, and a second plurality of temperature-measurement devices positioned proximal to a proximal end of the energy delivery member, the second plurality of temperature-measurement devices being thermally insulated from the energy delivery member.

Claims (36)

1. A method of operating an ablation system, comprising:

delivering energy at a frequency within an ablation radiofrequency range to at least one of a proximal electrode and a distal electrode, the proximal and distal electrodes positioned along a distal end of an intraluminal device, wherein the proximal electrode is separated from the distal electrode by a gap;

wherein the proximal electrode is operatively coupled to the distal electrode using a filtering element at the ablation radiofrequency range such that the proximal electrode and the distal electrode function like a single electrode, and wherein the proximal electrode and the distal electrode function as separate electrodes at high-resolution mapping frequencies;

receiving signals indicative of temperature from at least one temperature sensor positioned along the proximal or distal electrode;

determining, upon execution of instructions stored on a non-transitory storage medium by a hardware processor, determined temperature measurements from the signals received from the at least one temperature sensor; and

adjusting one or more treatment parameters of the ablation procedure based, at least in part, on the determined temperature measurements.

2. The method of claim 1 ,

wherein the ablation radiofrequency range is between 200 kHz and 10 MHz;

wherein adjusting the one or more treatment parameters of the ablation procedure is based, at least in part, on a predictive model or on at least one peak temperature measurement; and

wherein the at least one temperature sensor is configured to detect tissue temperature.

3. The method of claim 1 , wherein the ablation radiofrequency range is between 200 kHz and 10 MHz.

4. The method of claim 1 , wherein adjusting the one or more treatment parameters of the ablation procedure comprises automatically adjusting a power level.

5. The method of claim 1 , further comprising calculating a peak temperature based on the determined temperature measurements.

6. The method of claim 1 , wherein adjusting the one or more treatment parameters of the ablation procedure is based, at least in part, on a predictive model.

7. The method of claim 1 , wherein adjusting the one or more treatment parameters of the ablation procedure is based, at least in part, on peak temperature measurements.

8. The method of claim 1 , wherein the at least one temperature sensor is configured to detect tissue temperature.

9. The method of claim 1 , wherein the at least one temperature sensor is thermally insulated from the first electrode and the second electrode.

10. The method of claim 1 , wherein the at least one temperature sensor comprises a thermocouple.

11. A method of operating an ablation system, comprising:

delivering energy at a frequency within an ablation frequency range to at least one of a first electrode and a second electrode, the first and second electrodes positioned along a distal end of an ablation device, wherein the first electrode is operatively coupled to the second electrode using a filtering element at the ablation frequency range such that the first electrode and the second electrode function like a single electrode, and wherein the first electrode and the second electrode function as separate electrodes at high-resolution mapping frequencies;

receiving signals indicative of temperature from at least one temperature sensor positioned along the first or second electrode;

determining, upon execution of instructions stored on a non-transitory storage medium by a hardware processor, determined temperature measurements from the signals received from the at least one temperature sensor; and

adjusting at least one treatment parameter of the ablation procedure based, at least in part, on the determined temperature measurements.

12. The method of claim 11 , wherein the ablation frequency range is between 200 kHz and 10 MHz, and wherein the at least one temperature sensor is configured to detect tissue temperature.

13. The method of claim 11 , wherein the ablation frequency range is between 200 kHz and 10 MHz.

14. The method of claim 11 , wherein adjusting the at least one treatment parameter comprises automatically adjusting a power level.

15. The method of claim 11 , further comprising calculating a peak temperature based on the determined temperature measurements.

16. The method of claim 11 , wherein the at least one temperature sensor is configured to detect tissue temperature.

17. A method of operating an ablation system, comprising:

delivering energy at a frequency within an operating frequency range to at least one of a first electrode member and a second electrode member, the first and second electrode members positioned along on an ablation device, wherein the first electrode member is operatively coupled to the second electrode member using a filtering element at the operating frequency range such that the first electrode member and the second electrode member function like a single electrode, and wherein the first electrode member and the second electrode member function as separate electrodes at high-resolution mapping frequencies;

receiving signals indicative of temperature from at least one temperature sensor positioned along the first or second electrode member;

determining, upon execution of instructions stored on a non-transitory storage medium by a hardware processor, determined temperature measurements from the signals received from the at least one temperature sensor; and

adjusting at least one treatment parameter of the ablation procedure based, at least in part, on the determined temperature measurements.

18. The method of claim 17 , wherein the operating frequency range is between 200 kHz and 10 MHz.

19. The method of claim 17 , wherein adjusting the at least one treatment parameter comprises automatically adjusting a power level.

20. The method of claim 17 , wherein the at least one temperature sensor is configured to detect tissue temperature.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 11, 2018
From: PANESCU, DORIN; KOBLISH, JOSEF VINCENT; JOHNSON, JESSI E.; SCHULTHEIS, ERIC ANDREW
To: ADVANCED CARDIAC THERAPEUTICS, INC.
Reel/Frame 047138/0921 →
RELEASE OF SECURITY INTEREST Recorded Oct 11, 2018
From: ABBOTT LABORATORIES
To: EPIX THERAPEUTICS, INC., FORMERLY ADVANCED CARDIAC THERAPEUTICS, INC.
Reel/Frame 047218/0808 →
CHANGE OF NAME Recorded Aug 30, 2018
From: ADVANCED CARDIAC THERAPEUTICS, INC.
To: EPIX THERAPEUTICS, INC.
Reel/Frame 046988/0868 →
SECURITY INTEREST Recorded Feb 1, 2017
From: ADVANCED CARDIAC THERAPEUTICS, INC.
To: ABBOTT LABORATORIES
Reel/Frame 041146/0530 →
Continuity (9)
Continuation 15214376 · Jul 19, 2016
Continuation PCTUS2015061419 · Nov 18, 2015
Provisional Application 62081710 · Nov 19, 2014
Provisional Application 62094892 · Dec 19, 2014
Provisional Application 62135046 · Mar 18, 2015
Provisional Application 62135025 · Mar 18, 2015
Provisional Application 62138338 · Mar 25, 2015
Provisional Application 62211539 · Aug 28, 2015
Related Publication 20170189105A1 · Jul 6, 2017