IP Library Granted Patent US 10,285,679
Granted Patent B2
US 10,285,679 · App. 15/382,736 · Granted May 14, 2019

Micrograft for the treatment of intracranial aneurysms and method for use

Inventors: Stephen J. Hebert (San Francisco, CA); Bartosz Bojanowski (San Francisco, CA)
Assignee: Neurogami Medical, Inc.
A61B17/0057A61B17/1214A61B17/1215A61B17/12031A61B17/12113A61B17/12118A61B17/12145A61B17/12154A61B17/12172A61B17/12177A61F2/06A61F2/07B29D23/00B29D23/18A61B2017/0053A61B2017/00526A61B2017/00778A61B2017/00867A61B2017/00893A61B2017/00898A61B2017/00942A61B2017/1205A61B2017/12054A61B2090/0807A61B2090/3966A61F2/95A61F2002/077B29K2067/003B29K2105/0035B29K2105/25
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Quick Facts
Patent No.
US 10,285,679
App. No.
15/382,736
Granted
May 14, 2019
Kind
B2
Abstract

A device for occluding a vasculature of a patient including a micrograft having an absorbent polymeric structure with a lumen of transporting blood. The micrograft has a series of peaks and valleys formed by crimping. The occluding device is sufficiently small and flexible to be tracked on a guidewire and/or pushed through a microcatheter to a site within the vasculature of the patient. Delivery systems for delivering the micrografts are also disclosed.

Claims (19)

1. A vascular implant configured for placement in an intracranial aneurysm of a patient to induce blood stagnation in the aneurysm, the vascular implant comprising a core and a textile structure formed of filaments forming a tubular structure defining a wall, the textile structure attached to the core and extending over the core along a length of the core to cover the core, the textile structure being semi-porous to aid thrombus formation and having a density to provide stiffness to retain a non-linear heat set, wherein the vascular implant has a distal opening and a lumen extending therein encapsulated by the wall and blood contained therein to fill the lumen when positioned within a delivery catheter prior to placement in the intracranial aneurysm, the distal opening communicating with the lumen to provide blood flow proximally into the lumen.

2. The vascular implant of claim 1 , wherein the textile structure is composed of a plurality of yarns, the yarns spaced to enable blood flow between the yarns.

3. The vascular implant of claim 2 , wherein the yarns are composed of a series of the filaments, the filaments spaced to provide openings between the filaments for blood flow between the filaments.

4. The vascular implant of claim 3 , wherein the filaments are composed of PET.

5. The vascular implant of claim 2 , wherein the textile structure has a wavy form having a series of undulations.

6. The vascular implant of claim 2 , wherein the textile structure has an uneven braid surface.

7. The vascular implant of claim 3 , wherein individual yarns of the textile structure bulge outwardly to create the uneven surface to create localized hemodynamic turbulence and flow stagnation to enhance thrombus formation.

8. The vascular implant of claim 3 , wherein the filaments are oriented substantially transversely to a longitudinal axis of the vascular implant.

9. The vascular implant of claim 2 , wherein the vascular implant has a heat set coil shape.

10. A vascular implant configured for placement in an intracranial aneurysm of a patient to induce blood stagnation in the aneurysm, the vascular implant comprising a core having a lumen and a textile structure attached to the core and extending over the core along a length of the core to cover the core, the textile structure interlaced to form a fluid barrier while enabling blood flow through pores in the textile structure, the textile structure having a porosity to maintain capillarity, wherein the vascular implant has a distal opening and a lumen extending therein, the textile structure being tubular and a wall of the textile structure surrounding the lumen, and the vascular implant has blood contained therein to fill the lumen when positioned within a delivery catheter prior to placement in the intracranial aneurysm, the distal opening communicating with the lumen to provide blood flow proximally into the lumen.

11. The vascular implant of claim 10 , wherein the textile structure is composed of a plurality of yarns, the yarns spaced to enable blood flow between the yarns, the yarns are composed of a series of filaments, the filaments spaced to provide openings between the filaments.

12. The vascular implant of claim 11 , wherein the textile structure is non-expanding.

13. The vascular implant of claim 12 , wherein a capillary effect is created within the vascular implant when the textile structure is exposed to blood such that blood is transported in a proximal direction through the vascular implant and in various directions within the vascular implant to saturate the vascular implant with blood to aid thrombosis.

14. The vascular implant of claim 12 , wherein the textile structure has an uneven outer surface.

15. The vascular implant of claim 11 , wherein individual yarns of the textile structure bulge outwardly to create an uneven surface to create localized hemodynamic turbulence and flow stagnation to enhance thrombus formation and tissue growth.

16. The vascular implant of claim 13 , wherein the vascular implant has a secondary coil shape.

17. The vascular implant of claim 16 , wherein the secondary coil shape has a uniform transverse dimension along its length.

18. The vascular implant of claim 1 , wherein the textile structure is non-expanding.

19. The vascular implant of claim 5 , wherein the series of undulations forms a first series of longitudinally extending first peaks and first valleys, and filaments of the textile structure form second peaks and second valleys.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Jan 16, 2025
From: CEDAR'S CAPITAL LLC; FOLEY, KEVIN, DR.
To: NEUROGAMI MEDICAL, INC.
Reel/Frame 069898/0168 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 16, 2025
From: NEUROGAMI MEDICAL, INC.
To: KFNT HOLDINGS, LLC
Reel/Frame 069899/0608 →
SECURITY INTEREST Recorded Aug 1, 2023
From: NEUROGAMI MEDICAL, INC.
To: CEDAR'S CAPITAL LLC; FOLEY, KEVIN, DR.
Reel/Frame 064452/0642 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2017
From: HEBERT, STEPHEN J.; BOJANOWSKI, BARTOSZ
To: NEUROGAMI MEDICAL, INC.
Reel/Frame 041545/0855 →
Continuity (3)
Continuation 14997008 · Jan 15, 2016
Provisional Application 62105648 · Jan 20, 2015
Related Publication 20170095255A1 · Apr 6, 2017
Cited By (4)
US 12,251,112 US 12,285,175 US 12,303,153 US 12,414,775