IP Library Granted Patent US 10,556,123
Granted Patent B2
US 10,556,123 · App. 15/402,649 · Granted Feb 11, 2020

Method and apparatus for treatment of cutaneous and subcutaneous conditions

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Quick Facts
Patent No.
US 10,556,123
App. No.
15/402,649
Granted
Feb 11, 2020
Kind
B2
Abstract

The present invention provides method and apparatus for treating tissue in a region at depth while protecting non-targeted tissue by cyclically applying cooling to the patients skin, and preferably to the region, and by applying radiation to the patient's skin above the region to selectively heat tissue during and/or after cooling is applied. At least one of cooling and radiation may be applied by successively passing a continuous output applicator over the patient's skin. Treatment may also be enhanced by applying mechanical, acoustic or electrical stimulation to the region.

Claims (44)

1. A method for non-invasively treating subcutaneous fat tissue in a region of a patient's body, comprising:

cooling skin surface above a region of a patient's body prior to applying energy thereto;

applying energy, using an energy source, to skin surface to reach the region of a patient's body, said applied energy being of sufficient power and duration to raise temperature of said region above normal body temperature;

removing the application of energy to said region; and

repeating the steps of applying energy to said region and removing the application of energy to said region for a sufficient number of cycles to effect non-invasively any of a cosmetic or a therapeutic treatment in said tissue,

thereby increasing treatment time patient can tolerate compared with a treatment time patient can tolerate in absence of repeatedly cycling applying energy to and removing the application of energy to said region;

wherein during each of said cycles of applying energy and removing the application of energy the temperature of said region increases when applying energy to reach a peak value and decreases from said peak value when removing the application of energy, and

wherein the temperature of said region remains above normal body temperature during said repeated cycles of applying energy and removing the application of the energy.

2. The method of claim 1 , wherein the steps of cooling the skin surface above the region and repeating applying energy to said region and removing the application of energy to said region are performed during a total treatment time of at least 20 minutes.

3. The method of claim 2 wherein the cooled skin surface temperature is within the range between 0° C. and 25° C.

4. The method of claim 1 wherein the temperature of said region is raised to a temperature in a range from 42° C. to 47° C.

5. The method of claim 1 wherein cooling skin surface avoids damaging skin surface.

6. The method of claim 1 wherein the cosmetic treatment includes cellulite improvement.

7. The method of claim 1 , wherein said tissue is located below skin and at or above subcutis.

8. The method of claim 1 , wherein the cosmetic treatment includes fat reduction.

9. The method of claim 1 , wherein the cosmetic treatment includes skin tightening.

10. The method of claim 1 , wherein the cosmetic treatment includes skin lifting.

11. A method for non-invasively treating subcutaneous fat tissue in a region of a patient's body, comprising:

providing a stationary applicator;

cooling skin surface above a region of a patient's body prior to applying energy thereto;

applying energy from an energy source to skin surface, using the stationary applicator, to reach a region of a patient's body, said energy being of sufficient power and duration to raise the temperature of said region above normal body temperature;

reducing the energy applied from the energy source to said region; and

repeating the steps of applying energy to said region, using the stationary applicator, and reducing the energy applied to said region for a sufficient number of cycles to effect non-invasively any of a cosmetic or a therapeutic treatment in said tissue,

thereby increasing treatment time patient can tolerate compared with a treatment time patient can tolerate in absence of repeatedly cycling applying energy to and reducing the application of energy to said region;

wherein during each of said cycles of applying energy and reducing the energy applied the temperature of said region increases when applying energy to reach a peak value and decreases from said peak value when reducing the energy applied, and

wherein the temperature of said region remains above normal body temperature during said repeated cycles of applying energy and reducing the energy.

12. The method of claim 11 further comprising:

cooling the skin surface above the region for a selected duration.

13. The method of claim 12 wherein the cooled skin surface temperature is within the range between 0° C. and 25° C.

14. The method of claim 12 wherein cooling is applied prior to applying energy to the skin surface.

15. The method of claim 11 wherein the temperature of said region is raised to a temperature in a range from 42° C. to 47° C.

16. The method of claim 11 wherein the cosmetic treatment includes new collagen generation.

17. The method of claim 11 wherein the cosmetic treatment includes cellulite improvement.

18. The method of claim 11 , wherein said tissue comprises hypodermal tissue.

19. The method of claim 11 , wherein the cosmetic treatment includes fat reduction.

20. The method of claim 11 , wherein the cosmetic treatment includes skin tightening.

21. The method of claim 11 , wherein the cosmetic treatment includes skin lifting.

22. A method for non-invasively treating subcutaneous fat tissue in a region of a patient's body, comprising:

cycling (i) noninvasive application of energy, using an energy source, to a skin surface to reach the tissue region and (ii) removing or reducing the application of energy, wherein cycling the application of energy and removing or reducing the application of energy steps are performed;

raising temperature of the tissue region above normal body temperature during cycling;

repeating cycling for a sufficient number of cycles to effect fat reduction in the tissue region;

maintaining the temperature of the region above normal body temperature during the sufficient number of cycles; and

increasing a total treatment time patient can tolerate compared to treatment time patient can tolerate when cycling is not performed, wherein the total treatment time is at least 20 minutes.

23. The method of claim 22 further comprising cooling the skin surface above the region and increasing a total treatment time patient can tolerate compared to treatment time patient can tolerate when cycling is not performed, at least in part in response to cooling of skin surface to avoid damage thereto.

Assignments (10)
RELEASE OF SECURITY INTEREST Recorded Mar 1, 2024
From: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
To: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 066723/0227 →
TERMINATION AND RELEASE OF PATENTS Recorded Feb 29, 2024
From: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
To: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 066707/0957 →
ABL NOTICE AND CONFIRMATION OF GRANT OFSECURITY INTEREST IN PATENTS Recorded Jan 12, 2024
From: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
Reel/Frame 066222/0937 →
NOTICE AND CONFIRMATION OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Jan 7, 2020
From: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 051496/0579 →
RELEASE OF SECURITY INTEREST IN PATENT RIGHTS Recorded Dec 30, 2019
From: BANK OF AMERICA, N.A.
To: CYNOSURE, LLC
Reel/Frame 051447/0536 →
SECURITY INTEREST Recorded Oct 14, 2019
From: HOLOGIC, INC.; CYNOSURE, LLC; CYTYC CORPORATION; FAXITRON BIOPTICS, LLC; FOCAL THERAPEUTICS, INC.; GEN-PROBE INCORPORATED
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 050719/0701 →
PARTIAL RELEASE OF SECURITY INTEREST ASSIGNMENTS RECORDED AT REEL/FRAME 042261/0911 Recorded Oct 5, 2017
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 044127/0923 →
SECURITY INTEREST Recorded May 3, 2017
From: CYNOSURE, INC.; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 042261/0911 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 20, 2017
From: ALTSHULER, GREGORY B; YAROSLAVSKY, ILYA; BELIKOV, ANDREI V.; PRIKHODKO, KONSTANTIN
To: PALOMAR MEDICAL TECHNOLOGIES, INC.
Reel/Frame 042074/0834 →
MERGER Recorded Apr 20, 2017
From: PALOMAR MEDICAL TECHNOLOGIES, INC.
To: PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 042075/0587 →