IP Library Granted Patent US 10,500,413
Granted Patent B2
US 10,500,413 · App. 15/402,693 · Granted Dec 10, 2019

Method and apparatus for treatment of cutaneous and subcutaneous conditions

Inventors: Gregory B. Altshuler (Lincoln, MA); Konstantin Prikhodko (Viborg, RU); Andrei V. Belikov (St. Petersburg, RU); Ilya Yaroslavsky (North Andover, MA)
Assignee: PALOMAR MEDICAL TECHNOLOGIES, LLC
A61N5/0625A61B5/6843A61B18/203A61N1/20A61N1/328A61N1/36A61N5/0616A61N7/00A61B18/14A61B2018/00005A61B2018/00011A61B2018/00452A61B2018/00458A61B2018/00476A61N1/32A61N5/0613A61N2005/0659A61N2007/0008A61N2007/0034
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,500,413
App. No.
15/402,693
Granted
Dec 10, 2019
Kind
B2
Abstract

The present invention provides method and apparatus for treating tissue in a region at depth while protecting non-targeted tissue by cyclically applying cooling to the patients skin, and preferably to the region, and by applying radiation to the patient's skin above the region to selectively heat tissue during and/or after cooling is applied. At least one of cooling and radiation may be applied by successively passing a continuous output applicator over the patient's skin. Treatment may also be enhanced by applying mechanical, acoustic or electrical stimulation to the region.

Claims (28)

1. A non-invasive method for treating a patient's skin at a depth comprising:

providing an applicator;

applying electromagnetic radiation to skin surface, using the applicator, during a heating phase to increase a temperature of a target region at depth below the skin surface to be in a range from 42° C. to 47° C., wherein said target region comprises tissue about dermis-hypodermis junction;

cooling patient's skin surface below a damage temperature during a cooling phase;

reducing or removing energy applied from the applicator during the cooling phase following the heating phase such that the temperature of the target region decreases to a temperature above a first temperature; and

repeating the heating phase and the cooling phase to cycle the temperature of the target region to non-invasively effect fat reduction during a total treatment time of at least 20 minutes,

wherein the temperature of the target region is maintained above the first temperature during the step of repeating the heating phase and the cooling phase.

2. The method of claim 1 , wherein a combined duration of the heating phase and cooling phase is less than 11 seconds.

3. The method of claim 1 , wherein a combined duration of the heating phase and cooling phase is in a range from 5 seconds to 11 seconds.

4. The method of claim 1 , wherein the target region is at a depth of 2.5 mm below the skin surface.

5. The method of claim 1 , wherein the heating phase and cooling phase are cycled a sufficient number of times to induce new collagen generation in target region the patient's skin.

6. The method of claim 1 , wherein the electromagnetic radiation comprises optical energy.

7. The method of claim 6 , wherein the optical energy has at least one wavelength in the range from 800 nm to 1800 nm.

8. The method of claim 1 , wherein the step of cooling the patient's skin occurs during the heating phase.

9. The method of claim 1 , wherein the heating phase and the cooling phase are performed by scanning the applicator over the patient's skin surface.

10. The method of claim 1 , wherein the heating phase and the cooling phase are performed by the applicator, wherein the applicator is a stationary applicator.

11. The method of claim 1 , wherein the target region is at a depth between 2.5 mm and 7.5 mm.

12. The method of claim 1 , wherein said cosmetic treatment comprises tightening of the skin.

13. The method of claim 1 , wherein the first temperature is 40° C.

14. The method of claim 1 , wherein the first temperature is a discomfort temperature.

15. The method of claim 1 , wherein the first temperature is a damage temperature.

16. A non-invasive method for treating a patient's skin at a depth comprising:

providing a stationary applicator;

applying electromagnetic radiation to skin surface, using the stationary applicator, during a heating phase to increase a temperature of a target region at depth below the skin surface to be in a range from 42° C. to 47° C., wherein said target region comprises tissue about dermis-hypodermis junction;

cooling patient's skin surface, using the stationary applicator, below a damage temperature during a cooling phase;

reducing or removing energy applied from the applicator during the cooling phase following the heating phase such that the temperature of the target region decreases to a temperature above a first temperature; and

repeating the heating phase and the cooling phase to cycle the temperature of the target region to non-invasively effect a fat reduction, wherein heating phase and cooling phase are a cycled during a total treatment time of at least 20 minutes,

wherein the temperature of the target region is maintained above the first temperature during the step of repeating the heating phase and the cooling phase.

Assignments (10)
RELEASE OF SECURITY INTEREST Recorded Mar 1, 2024
From: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
To: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 066723/0227 →
TERMINATION AND RELEASE OF PATENTS Recorded Feb 29, 2024
From: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
To: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 066707/0957 →
ABL NOTICE AND CONFIRMATION OF GRANT OFSECURITY INTEREST IN PATENTS Recorded Jan 12, 2024
From: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
Reel/Frame 066222/0937 →
NOTICE AND CONFIRMATION OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Jan 7, 2020
From: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 051496/0579 →
RELEASE OF SECURITY INTEREST IN PATENT RIGHTS Recorded Dec 30, 2019
From: BANK OF AMERICA, N.A.
To: CYNOSURE, LLC
Reel/Frame 051447/0536 →
SECURITY INTEREST Recorded Oct 14, 2019
From: HOLOGIC, INC.; CYNOSURE, LLC; CYTYC CORPORATION; FAXITRON BIOPTICS, LLC; FOCAL THERAPEUTICS, INC.; GEN-PROBE INCORPORATED
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 050719/0701 →
PARTIAL RELEASE OF SECURITY INTEREST ASSIGNMENTS RECORDED AT REEL/FRAME 042261/0911 Recorded Oct 5, 2017
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 044127/0923 →
SECURITY INTEREST Recorded May 3, 2017
From: CYNOSURE, INC.; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 042261/0911 →
MERGER Recorded Apr 20, 2017
From: PALOMAR MEDICAL TECHNOLOGIES, INC.
To: PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 042075/0587 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 20, 2017
From: ALTSHULER, GREGORY B; YAROSLAVSKY, ILYA; BELIKOV, ANDREI V.; PRIKHODKO, KONSTANTIN
To: PALOMAR MEDICAL TECHNOLOGIES, INC.
Reel/Frame 042074/0834 →
Continuity (5)
Continuation 14588746 · Jan 2, 2015
Continuation 11865367 · Oct 1, 2007
Continuation 10465757 · Jun 19, 2003
Provisional Application 60389871 · Jun 19, 2002
Related Publication 20170182335A1 · Jun 29, 2017