PPARγ agonists for treatment of multiple sclerosis
View Patent ↗Methods of treatment of multiple sclerosis (MS) with PPARγ agonists, and in particular with the compound of formula (I) known as INT131:
1. A method of treating grey matter atrophy in a patient in need thereof comprising administering to said patient at regular dosing intervals a pharmaceutical composition comprising a therapeutically effective amount of a compound of formula (I),
or a pharmaceutically acceptable salt thereof.
2. The method of claim 1 , wherein the regular dosing interval is once per day.
3. The method of claim 1 , wherein the therapeutically effective amount of the compound of formula (I) is from about 1 to about 3 milligrams.
4. The method of claim 3 , wherein the amount of the compound of formula (I) is about 1 milligrams per day or about 3 milligrams.
5. The method of claim 4 , wherein the amount of the compound of formula (I) is about 1 milligrams.
6. The method of claim 4 , wherein the amount of the compound of formula (I) is about 3 milligrams.
7. The method of claim 1 , wherein the regular dosing interval is once per day and the therapeutically effective amount of the compound of formula (I) is from about 1 to about 3 milligrams.