Mass spectrometers having real time ion isolation signal generators
Apparatuses, systems, and methods for performing mass analysis are disclosed. One such apparatus may include an ion trap device for use in a mass analysis system. The ion trap device may comprise an ion trap and a signal generator for applying an excitation signal to the ion trap. The signal generator may include a plurality of oscillators each configured to selectively generate a corresponding sinusoid signal to be selectively combined to form the excitation signal.
1. An ion trap device for use in a mass analysis system, the ion trap device comprising:
an ion trap; and
a signal generator for applying an excitation signal to the ion trap, wherein the signal generator includes a plurality of oscillators each configured to selectively generate a corresponding sinusoid signal to be selectively combined to form the excitation signal.
2. The ion trap device of claim 1 , wherein the sinusoid signal is a digital signal.
3. The ion trap device of claim 1 , wherein each oscillator is configured to generate its sinusoid signal based on a lookup table.
4. The ion trap device of claim 1 , wherein each oscillator is configured to generate its sinusoid signal having at least one of a predetermined frequency, a predetermined amplitude, or a predetermined phase.
5. The ion trap device of claim 1 , wherein each oscillator is configured to modify at least one of a frequency, an amplitude, or a phase of its sinusoid signal in real time.
6. The ion trap device of claim 1 , further comprising a controller communicatively connected to the plurality of oscillators, wherein the controller is configured to turn on or off one or more oscillators in real time.
7. The ion trap device of claim 1 , wherein the signal generator further comprises a controller communicatively connected to the plurality of oscillators, wherein the controller is configured to turn on or off one or more oscillators in real time.
8. The ion trap device of claim 1 , wherein the signal generator further comprises a digital summing device to sum the plurality of sinusoid signals to form a digital waveform.
9. The ion trap device of claim 8 , wherein the signal generator further comprises a digital-to-analog converter to convert the digital waveform to an analog waveform.
10. The ion trap device of claim 9 , wherein the signal generator further comprises an amplifier to amplify the analog waveform to generate the excitation signal.
11. The ion trap device of claim 1 , wherein the signal generator is configured to apply the excitation signal to eject ions of a given mass from the ion trap.
12. The ion trap device of claim 1 , wherein the plurality of oscillators are embedded into the signal generator.
13. A mass analysis system, comprising:
an ion trap device, including:
an ion trap;
a signal generator for applying an excitation signal to the ion trap, wherein the signal generator includes a plurality of oscillators each configured to selectively generate a corresponding sinusoid signal to be selectively combined to form the excitation signal; and
an ion detector.
14. The mass analysis system of claim 13 , further comprising an ionization device for providing ions of a sample to be analyzed.
15. A method for generating an excitation signal to eject a particular ion from an ion trap, comprising:
generating a plurality of sinusoid signals that include at least one frequency component corresponding to the particular ion to be ejected from the ion trap;
summing the plurality of sinusoid signals to form a digital waveform;
converting the digital waveform to the excitation signal; and
applying the excitation signal to the ion trap, such that the particular ion will be ejected.
16. The method of claim 15 , wherein converting the digital waveform to the excitation signal includes:
converting the digital waveform to an analog waveform; and
amplifying the analog waveform to the excitation signal.
17. The method of claim 15 , wherein generating the plurality of sinusoid signals includes setting at least one of a frequency, an amplitude, or a phase for each sinusoid signal.
18. The method of claim 15 , further comprising modifying at least one of a frequency, an amplitude, or a phase of one or more sinusoid signals in real time.
19. The method of claim 15 , further comprising turning on or off one or more sinusoid signals in real time.
20. The method of claim 15 , wherein generating the plurality of sinusoid signals includes generating the plurality of sinusoid signals based on a lookup table.
21. The method of claim 15 , wherein applying the excitation signal includes applying the excitation signal during ionization or ion collection to prevent trapping of one or more ions.
22. The ion trap device of claim 1 , wherein the ion trap includes a 3D quadrupole ion trap, a linear ion trap (LIT), or a cylindrical ion trap (CIT).