Compensating for disruptions in breathing gas flow measurement

1. A therapeutic gas delivery apparatus for use with a ventilator, the apparatus comprising:

a therapeutic gas injector module configured to be placed in fluid communication with a breathing circuit affiliated with the ventilator, the therapeutic gas injector module including a breathing gas flow inlet, a therapeutic gas flow inlet, and a combined breathing gas and therapeutic gas flow outlet for providing a combined flow of breathing gas and therapeutic gas to a patient, in need thereof;

a first flow sensor configured to sense breathing gas flow rate data; and

a controller configured to control the delivery flow rate of the therapeutic gas based on a first mode, and upon detection of a disruption of the sensed breathing gas flow rate data, configured to control delivery flow of the therapeutic gas based on the historical breathing gas flow rate data previously sensed by the first flow sensor and stored in the memory.

2. The apparatus of claim 1 , wherein the controller comprises:

a memory configured to store historical flow rate data related to the sensed breathing gas flow rate data by the first flow sensor; and

a processor configured to detect a disruption of the sensed breathing gas flow rate data from the first flow sensor, and

wherein the first flow sensor is a gas inspiratory flow sensor, and the controller is configured to use the historical breathing gas flow rate based on a historical average upon detection of a disruption in the form of a failure of an operation of a gas inspiratory flow sensor.

3. The apparatus of claim 2 , wherein the historical flow rate data includes one or more of a moving average breathing gas flow rate, a moving median breathing gas flow rate, and/or a gas flow rate waveform.

4. The apparatus of claim 2 , wherein the historical flow rate data is stored over a period in the range from 10 seconds to 5 minutes.

5. The apparatus of claim 1 , wherein the sensed breathing gas flow rate is received from the injector module and/or the ventilator.

6. The apparatus of claim 1 , wherein the therapeutic gas is inhaled Nitric Oxide.

7. The apparatus of claim 1 , wherein the sensed breathing gas flow rate data comprises first breathing gas flow rate data and second breathing gas flow rate data, and wherein the first breathing second gas flow rate data is received from the injector module and/or the second breathing gas flow rate data is received from the ventilator.

8. The apparatus of claim 7 , wherein the controller compares respective flow rate data from the first breathing gas flow rate data with the second breathing gas flow rate data.

9. The apparatus of claim 1 , wherein the controller is configured to automatically resume delivery of a flow of therapeutic gas based on the first mode, upon detection and/or input that the first flow sensor has been at least one of reconnected, replaced, and/or serviced.

10. The apparatus of claim 1 , wherein the controller is further configured to utilize at least one of data smoothing and/or low-pass filtering to remove outlying stored flow data points.

11. A method for delivery of therapeutic gas to a patient, the method comprising:

controlling via a controller therapeutic gas flow to a patient in a first mode;

receiving, via a sensor, sensed flow rate data of breathing gas flow;

storing in a memory historical flow rate data related to the received breathing gas flow rate data by the sensor;

detecting a disruption of the sensed breathing gas flow rate data from the sensor; and

controlling via the controller the therapeutic gas flow in a temporary mode instead of the first mode, based on the received breathing gas flow rate data.

12. The method of claim 11 , wherein the historical sensed flow rate data comprises one or more of a moving average breathing gas flow rate, a moving median breathing gas flow rate, and/or a gas flow rate waveform.

13. The method of claim 12 , wherein storing the historical flow data includes storing the historical flow rate data over a period in the range from 10 seconds to 5 minutes.

14. The method of claim 11 , further comprising:

returning to the first mode when a discontinuance of the disruption is detected.

15. The method of claim 14 , wherein:

receiving the received flow rate data includes receiving a first received flow rate data and a second received flow rate data from, and

detecting the disruption includes detecting the disruption by comparing respective flow rate data between the two or more received flow rate data groups.

16. An apparatus for delivery of nitric oxide and therapeutic gas to a patient, comprising:

a controller configured to control therapeutic gas flow to a patient in a first mode and to receive sensed flow rate data of breathing gas flow;

a memory configured to store received breathing gas flow rate data related to previous sensed historical flow data;

a detector configured to detect a disruption of received breathing gas flow rate data from the received breathing gas flow rate data; and

wherein the controller is further configured to retrieve historical flow rate data, and to control therapeutic gas flow rate in a temporary mode, instead of the first mode, based on the historical flow rate.

17. The apparatus of claim 16 , wherein the historical sensed flow rate data comprises one or more of a moving average breathing gas flow rate, a moving median breathing gas flow rate, and/or a breathing gas flow waveform.

18. The apparatus of claim 17 , wherein the historical flow rate data is stored over a period in the range from 10 seconds to 5 minutes.

19. The apparatus of claim 16 , wherein the controller is further configured return to the first mode when a discontinuance of the disruption is detected.

20. The apparatus of claim 16 , wherein:

the received sensed flow rate data comprises a first received flow rate data and a second received flow rate data from two or more sensors, and

detecting the disruption includes comparing flow rate data between the two or more received flow rate data.