Gel containing pirfenidone

1. A method for treating fibrotic lesions in a patient in need thereof, the method comprising cutaneous administration to the patient of a Pirfenidone gel consisting of 8% Pirfenidone, 0.5% of a viscous agent, 20% of a solubilizer, 11.5% of a non ionic solubilizer, 0.5% of a conserving agent, 0.5% of a neutralizer agent and 59% of purified water, thereby treating the fibrotic lesions in the patient.

2. The method of claim 1 , wherein

(a) the viscous agent in the Pirfenidone gel is selected from the group consisting of a Carbomer 940, Carbomer Interpolymer Type A, a cellulose derivative, a gum, and a poloxamer;

(b) the solubilizer in the Pirfenidone gel is selected from the group consisting of N-methylpyrrolidone, ethyl alcohol, and propylene glycol;

(c) the conserving agent in the Pirfenidone gel is selected from the group consisting of diazolidinyl urea, iodopropynyl butylcarbamate, methylparaben, propylparaben, and mixes of these conserving agents; and

(d) the neutralizer agent in the Pirfenidone gel is selected from the group consisting of primary, secondary and tertiary mono-, bi-, and triethanolamine aliphatic amines, and a hydroxide alkaline metal.

3. The method of claim 2 , wherein the viscous agent in the Pirfenidone gel is Carbomer 940, the solubilizer is N-methylpyrrolidone, the conserving agent is diazolidinyl urea, and the neutralizer agent is triethanolamine.

4. The method of claim 2 , wherein the viscous agent in the Pirfenidone gel is Carbomer 940, the solubilizer is N-methylpyrrolidone, the conserving agent is iodopropynyl butylcarbamate, and the neutralizer agent is triethanolamine.

5. The method of claim 2 , wherein the hydroxide alkaline metal in the Pirfenidone gel is sodium hydroxide.